Protein Info for LRK53_RS13595 in Rhodanobacter sp000427505 FW510-R12

Annotation: polyphosphate kinase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 697 PF13089: PP_kinase_N" amino acids 20 to 126 (107 residues), 110.4 bits, see alignment E=1.4e-35 TIGR03705: polyphosphate kinase 1" amino acids 20 to 693 (674 residues), 906.1 bits, see alignment E=7.5e-277 PF02503: PP_kinase" amino acids 135 to 311 (177 residues), 184.4 bits, see alignment E=4.3e-58 PF17941: PP_kinase_C_1" amino acids 346 to 506 (161 residues), 243.2 bits, see alignment E=2.7e-76 PF13091: PLDc_2" amino acids 391 to 504 (114 residues), 30.5 bits, see alignment E=7.2e-11 PF13090: PP_kinase_C" amino acids 516 to 688 (173 residues), 207.9 bits, see alignment E=1.9e-65

Best Hits

Swiss-Prot: 62% identical to PPK1_XYLFA: Polyphosphate kinase (ppk) from Xylella fastidiosa (strain 9a5c)

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 63% identity to smt:Smal_0822)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.4.1

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (697 amino acids)

>LRK53_RS13595 polyphosphate kinase 1 (Rhodanobacter sp000427505 FW510-R12)
MAHPSPTPPDATDLSAPGLYLSRELAALEFNFRVLAMASDSTVPLLERLRYLSIVANNLD
EFFEVRVAMLKHHHAYGSAAPGPDGISSGELLARIRSRVLDLVAAQYAAWQEQISPQLDA
EQIHILTRKSWSPRQHRWLRGYFEHEVLPVLSPLGLDPAHPFPRILNKTLNIAVVLRGRD
AFGHEGHMALVRAPRSLPRIIRVPAEVSGPGEHFVFLAELLQAFVDLMFPGLKVVGSYQF
RVTRNSELIVEEAEVENLALALSEELVGRGYARPVRLEIANDCPKAITAMLTHNFELDDA
DVYRCDGPVNIIRAGLIYDWLDRPELKFPRFNPQLPPALESSRNKFDVIGQHDVLLHHPY
QSFNAVIDLLRQAAADPQVLAIKQTLYRAGEDTPLVDLLVEAARNGKDVTVVIELRARFD
EEANIRLATRLQEAGVQVVYGVVGYKTHAKMMLIVRREGEALRRYVHLSTGNYHQANSRM
YTDIGLMTANPEIGEDLHKVFQQLSGLGPIIELKRLLHSPFTLYPSVLAKIERETAHAQA
GRPARIVAKLNALNEARVIEALYRASQAGVEIDLIVRGACTLRPGLPGVSERIRVRSIVG
RFLEHSRVYWFANDGDAEIYCASADWMERNLMRRIEVAFPILDPELAARVFEETLANGLA
DNTQAWRLGADGRYTRAEPGDNPPYSAQQGLLERYNT