Protein Info for LRK53_RS13480 in Rhodanobacter sp000427505 FW510-R12

Annotation: bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 TIGR00197: YjeF family N-terminal domain" amino acids 19 to 212 (194 residues), 129.9 bits, see alignment E=1e-41 PF03853: YjeF_N" amino acids 32 to 191 (160 residues), 137.5 bits, see alignment E=4.5e-44 TIGR00196: YjeF family C-terminal domain" amino acids 229 to 485 (257 residues), 228.9 bits, see alignment E=7.7e-72 PF01256: Carb_kinase" amino acids 246 to 482 (237 residues), 216.8 bits, see alignment E=3.2e-68

Best Hits

KEGG orthology group: None (inferred from 53% identity to aeh:Mlg_0568)

Predicted SEED Role

"NAD(P)HX epimerase / NAD(P)HX dehydratase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (499 amino acids)

>LRK53_RS13480 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase (Rhodanobacter sp000427505 FW510-R12)
MPAHPYSRNLHTVEQLRVMERAALAALGISGHGLMRRAASTALNSLRRHWPQLQHICIHC
GPGNNGGDGFLLGVLAREAGLRVELVTLTAASHGDAAAARAAWESAGGRVRLWDVHSELP
DAELHVDALYGIGLNRAPELAAARLIEAINDSGHPVLALDVPSGLDADTGNCPGAAIRAD
VTVTFIAGKRGLHTGRAADQAGALELATLGVPDSVYVDALPDAQLLVAEALPPRARYANK
GNYGHVLVIGGEHGMAGAVRLAGESALRAGAGLVSVATRAGHVSALNAARPELMAHGVDG
PQALLPLLERASVLALGPGLGQAAWGHALWLTALDAGKPLVLDADGLNLLAREPRRFGAP
TVLTPHPGEAARLLGVAAASVERDRFAAARELARRHDAVVVLKGAGSLIADSDGRLDVCP
WGNPGMASGGMGDLLTGIVAGLLAQGCSAWQAACLGTGLHARAGDRAAQQGERGLLASDL
LAHLRALGNGMTGYEREHD