Protein Info for LRK53_RS13370 in Rhodanobacter sp000427505 FW510-R12

Annotation: S8 family serine peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 952 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF00082: Peptidase_S8" amino acids 80 to 368 (289 residues), 136.9 bits, see alignment E=1.3e-43 TIGR02601: autotransporter-associated beta strand repeat" amino acids 406 to 437 (32 residues), 26.9 bits, see alignment (E = 1.6e-10) PF12951: PATR" amino acids 407 to 437 (31 residues), 34 bits, see alignment (E = 3.6e-12) PF03797: Autotransporter" amino acids 681 to 932 (252 residues), 129.4 bits, see alignment E=3e-41

Best Hits

KEGG orthology group: None (inferred from 41% identity to psu:Psesu_1636)

Predicted SEED Role

"Outer membrane stress sensor protease DegS" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (952 amino acids)

>LRK53_RS13370 S8 family serine peptidase (Rhodanobacter sp000427505 FW510-R12)
MKVLDSGWRRREMALLVAMALGLSACGGGGGSKPTPPPVVPTSPPPAPPPSPPPSAQPPL
DAQLSITRASGAQSLGYTGVGVTIGMVDSGIMRSNPTVAGRVTQELIYVDPTVNKTAIDD
VVGHGTWVSEIAAGTGFAKFPGGIAPRASLVSARIISDVTPKDDGSGQGNAVTAADAAFF
AQTLNPALINAGVQVMNNSWGGIYWDTTNASINQAFGQAYQPFVVQHGGLVVFAAGNESR
TSPSDIASLPTVAPGLGLDKGWLVAVALDSNHPTQLASYSNACGRTMNYCLAAPGDVIVL
DKDTTASTTNPSYWVVSGTSFAAPQVSGAAALVWQAFPYFSNDLVRQTLLGTARDLGAPG
PDPTFGYGALDVFAAVQGPARFDWGDVTVNFSGTSTWGNPISGAGGLIKQGPGRLNLWGG
ESSYTGLTQVQGGTLAVAGLHSPVEIGAAGTLMSASTQLNPTGFSVYNSVTNAGVLVVSQ
GDVHLSGNYLQQGSGRMAVSLGSQLYVNGTATLSGGDLYVYGANANYTLNSHTTVLTANA
GLTGTFSALNTAPGVALTATLGYDASNAWLDVQQVNLSQIQGLPYTAASFGAALRTQSAF
QQINSQLQGVASGTSVGTGFVEGAANLQHAVSTEVMQRSLESLSGQLHAASAAMTFEAID
AGTRALSDRFDRLLDAPQAGAWTQSLGYHGGMSRSGYGHVGYDLSGALVGQDLRVGSNGV
AGYALSQSRSLGRLAESADQGRSHALEGMLYGGMVHGSWYAMGRFGIGSYRETMRRQLQL
GDQFAGVASDVHGRYGVAYGESGYRFTLGRTQLTPYMNLQYAQIRRDGFNELGAYGFGLK
SAAQSTARWQAGAGLRVTREWALPGGGSLAMQGRMLWQQSFGLRGEAFDASFSGVNQFAP
VGGIGLSRYGGMLGTTLDWKMTPHASLQFGYDRYLGQGRQAQMASASFSWAF