Protein Info for LRK53_RS12995 in Rhodanobacter sp000427505 FW510-R12

Annotation: Na+/H+ antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 545 signal peptide" amino acids 1 to 6 (6 residues), see Phobius details transmembrane" amino acids 7 to 24 (18 residues), see Phobius details amino acids 36 to 45 (10 residues), see Phobius details amino acids 47 to 47 (1 residues), see Phobius details amino acids 53 to 70 (18 residues), see Phobius details amino acids 83 to 107 (25 residues), see Phobius details amino acids 113 to 135 (23 residues), see Phobius details amino acids 156 to 176 (21 residues), see Phobius details amino acids 182 to 203 (22 residues), see Phobius details amino acids 215 to 233 (19 residues), see Phobius details amino acids 239 to 258 (20 residues), see Phobius details amino acids 270 to 291 (22 residues), see Phobius details amino acids 311 to 336 (26 residues), see Phobius details amino acids 357 to 381 (25 residues), see Phobius details amino acids 393 to 414 (22 residues), see Phobius details TIGR00831: Na+/H+ antiporter" amino acids 11 to 543 (533 residues), 402.9 bits, see alignment E=9.8e-125 PF00999: Na_H_Exchanger" amino acids 13 to 418 (406 residues), 203.1 bits, see alignment E=3.3e-64

Best Hits

KEGG orthology group: K03316, monovalent cation:H+ antiporter, CPA1 family (inferred from 73% identity to azo:azo0346)

Predicted SEED Role

"Na+/H+ antiporter" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (545 amino acids)

>LRK53_RS12995 Na+/H+ antiporter (Rhodanobacter sp000427505 FW510-R12)
MNSIEVALAMLLAVVGSGYLVRMLPFSLPLPLVQIGLGAVITGVFKHGVALDPAIFFLLF
LPPLLFLDGWRIPKDGLMRDRGAILALALGLVVFTVVGVGFLIHWLIPAMPLAVAFALAA
IVSPTDPVAVSSITARVPIPKRLMHILEGESLLNDASGLVCFRFAVAAMTGSFSLLSASL
TFLWVALAGFGVGVAFTVAVSFAQRWLSRHFGQEAGSPILISLLIPFGAYLLAEQVHASG
ILAAVAAGITMSYVELSGRLLATTRVQRTAVWNTVQFALNGIMFVLLGEQLPASLQGAME
SVAQSGHRNPWWLLVYALAINIGLALLRLAWVWISLRLNVLKAHHHGTPVSRPHWRLLLA
TSLAGVRGAITLAGVMTLPLLLPDGTPFPARELTIFLATAVILLSLLVASIGLPPLLKGL
QLPPEPAVQREENLARRSAAKAAIAAVEKAQHELLEKAPAGDVDTYTNAATRVIALYQHW
LDEDASSEDEARQLRKADTAERELRLAALQGQREAVFELARHRRISDEVSRRLVREIDLQ
EARYR