Protein Info for LRK53_RS12175 in Rhodanobacter sp000427505 FW510-R12

Annotation: sulfate ABC transporter permease subunit CysT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 60 to 84 (25 residues), see Phobius details amino acids 96 to 118 (23 residues), see Phobius details amino acids 136 to 156 (21 residues), see Phobius details amino acids 186 to 206 (21 residues), see Phobius details amino acids 240 to 264 (25 residues), see Phobius details TIGR00969: sulfate ABC transporter, permease protein" amino acids 6 to 265 (260 residues), 320.9 bits, see alignment E=7.3e-100 TIGR02139: sulfate ABC transporter, permease protein CysT" amino acids 7 to 270 (264 residues), 392.3 bits, see alignment E=1.2e-121 PF00528: BPD_transp_1" amino acids 73 to 268 (196 residues), 92.6 bits, see alignment E=1.3e-30

Best Hits

Swiss-Prot: 52% identical to CYST_SYNY3: Sulfate transport system permease protein CysT (cysT) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K02046, sulfate transport system permease protein (inferred from 66% identity to gur:Gura_3893)

MetaCyc: 53% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysU (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysT" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (276 amino acids)

>LRK53_RS12175 sulfate ABC transporter permease subunit CysT (Rhodanobacter sp000427505 FW510-R12)
MSMRHRVLPGFGLSLGYALAYLGLIVLLPLAALVWKASGIGLQGMVHLLAAPRTLAALKL
SFGGALAAALINVVVGLLVGWALVRYRFPGRRLLDALIDLPFALPTAVAGIALTALYAPN
GWLGRWLEPLGIKVAYTPWGVLLAMVFVGFPFVVRTLEPVLQSLERDVEEAAESLGATRW
QTFTRVILPLLIPTLLTGFALALARAVGEYGSVIFIAGNIPMRSEIVPLLIVQKLEEFDY
AGAAALGVVMLAFSFLLLVLVALLQRWSRRWAERAA