Protein Info for LRK53_RS11965 in Rhodanobacter sp000427505 FW510-R12

Annotation: DNA repair protein RecO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 PF11967: RecO_N" amino acids 1 to 78 (78 residues), 69.9 bits, see alignment E=1.5e-23 TIGR00613: DNA repair protein RecO" amino acids 8 to 219 (212 residues), 75.8 bits, see alignment E=1.8e-25 PF02565: RecO_C" amino acids 87 to 226 (140 residues), 71 bits, see alignment E=1e-23

Best Hits

Swiss-Prot: 47% identical to RECO_XANAC: DNA repair protein RecO (recO) from Xanthomonas axonopodis pv. citri (strain 306)

KEGG orthology group: K03584, DNA repair protein RecO (recombination protein O) (inferred from 47% identity to xac:XAC1327)

Predicted SEED Role

"DNA recombination and repair protein RecO" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (241 amino acids)

>LRK53_RS11965 DNA repair protein RecO (Rhodanobacter sp000427505 FW510-R12)
MRLEQQPAYVLHARAYRETSLLLECLTREHGRLGVVARGVRGERSRLRRAQLEPFQPLAM
DLLLRGELATLTAVETVGTPTRLPGDAGLAGLYLNELVVRLTGRQDPYPRLFDAYARTLA
RLAAGESLAWSLRRFERDLLEAIGYGLQLLHDAESGEPLEPSACYRYQVEQGAVRCVAST
PRALRGSDLLALGQDSMPDAHGLKTLRDLMREVIRFHLGGSELRAWRVLATAVSGRKAPS
G