Protein Info for LRK53_RS11400 in Rhodanobacter sp000427505 FW510-R12

Annotation: DNA repair protein RecN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 557 TIGR00634: DNA repair protein RecN" amino acids 1 to 552 (552 residues), 474.3 bits, see alignment E=3.6e-146 PF02463: SMC_N" amino acids 2 to 511 (510 residues), 53.7 bits, see alignment E=2e-18 PF13476: AAA_23" amino acids 5 to 49 (45 residues), 29.8 bits, see alignment 9.6e-11

Best Hits

Swiss-Prot: 48% identical to RECN_XYLFT: DNA repair protein RecN (recN) from Xylella fastidiosa (strain Temecula1 / ATCC 700964)

KEGG orthology group: K03631, DNA repair protein RecN (Recombination protein N) (inferred from 55% identity to psu:Psesu_1658)

Predicted SEED Role

"DNA repair protein RecN" in subsystem DNA-replication or DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (557 amino acids)

>LRK53_RS11400 DNA repair protein RecN (Rhodanobacter sp000427505 FW510-R12)
MLTSLYVRHFAVVEAAEVAFGPGLTVVSGETGAGKSLLVDALMLLAGARADSGMVRAGSD
RAELAAEFDLAELPAARDWLQREELDEDGGCQLRRVIRAEGSSKAWINGRPANARQLGEL
AALLVEIHGQHEHQALLSRPHQLALLDAYAGHDELLAQVRGNAVRWRELGTRMRKLSGGD
DRDQRIELLRHEIGELEKWALPAAELAELETQHKRLANAGRLAEGTAGVVELLDGDSEFA
LRRALGRAQAELGKLAALDERLNPLLELLDNAGIQLGEAADGLARYAQDVDLDPERFTEV
DNHLARLHELSRRHRLPAAELHDRLAVLQAELAELEGAGDVLEQLMAQRERLRGDYTHAA
AKLSEARAAAAARLGDEVSVLMGELGMVGGLLRVELEPSSGDEPDPQGGERCELLVSANP
GQPPRPLRKVASGGELARISLAIEVVTLGKDTVGSMIFDEVDSGIGGAVAEVVGQKLRAL
GAQRQVLCVTHLPQVAAQGHAHLKVSKHSDGDSTHTQIEALDAAGRRDELARMLGGLEIT
RETRAHARQMLERAQSA