Protein Info for LRK53_RS10615 in Rhodanobacter sp000427505 FW510-R12

Annotation: MMPL family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 802 transmembrane" amino acids 26 to 45 (20 residues), see Phobius details amino acids 235 to 256 (22 residues), see Phobius details amino acids 263 to 287 (25 residues), see Phobius details amino acids 293 to 316 (24 residues), see Phobius details amino acids 337 to 360 (24 residues), see Phobius details amino acids 367 to 392 (26 residues), see Phobius details amino acids 425 to 444 (20 residues), see Phobius details amino acids 642 to 674 (33 residues), see Phobius details amino acids 686 to 709 (24 residues), see Phobius details amino acids 735 to 756 (22 residues), see Phobius details amino acids 764 to 788 (25 residues), see Phobius details PF03176: MMPL" amino acids 202 to 423 (222 residues), 29.5 bits, see alignment E=5.7e-11 amino acids 620 to 794 (175 residues), 43.8 bits, see alignment E=2.6e-15 PF02460: Patched" amino acids 247 to 376 (130 residues), 27.6 bits, see alignment E=3.4e-10 PF12349: Sterol-sensing" amino acids 263 to 379 (117 residues), 24.5 bits, see alignment E=3.3e-09

Best Hits

Predicted SEED Role

"FIG005548: transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (802 amino acids)

>LRK53_RS10615 MMPL family transporter (Rhodanobacter sp000427505 FW510-R12)
MTKPDTKLSPARHVVNAFSWLLFNHRPVMLVLFALITGGLAWSSTNLRLDPGFNKMIPLQ
HSYMRTFTKYRDTFGGANRIVVALMKKRGNIYQPGFMQLLKGATSDVFFIPGVDRTSVQS
LFTPNTRFIEITPQGFVGGNVVPANFAGTPQQLLAVRQNVEKAGLVGHLVANNLNGALIT
ASLLDVDPKTGKQLDDINIAKNLEQLRDKYDRLGDKDGVTVHIIGFAKEVGDIAAGIRGV
IVFFGIAFLITALLLRWYTRSTALALIALFCALLPVLWLLGVLPLFGFGVDPFSLLVPFL
IFAIGVSHAVQMTNAWRTAAIAGESGLQASRTAFDQLFIPGVLALLTNALGFLVILLIKI
QIVQELAITASIGVTLMIITNKMVLPIALSYLPAHPDHLRRLTRDESRSEKIWQFMSGFA
TRRRGGVVIGIALVLTGLGAWGATGLKTGDLGTGVPELRANSRYNIDSRVITDNFRTGVD
VLSVIVQSHGIDGACADYRIMDAMDAFEWKMSSIPGVASAMSLVDVAKIGNAGFNEGDIK
WQSIAHNRDVLAQSTSQVETSSGLLNADCSAMQILLFPSNHRGTTLAGIVTAVKAWNTMF
KSSAKYVPVAEHMSFLLASGNDGIMAATNEAVDNADTMELVALFSAIALICLLTFRSFVA
VACILIPLALVALLNNALMATLDIGMKISTLSVIALGIGVGVDYGIYIFDRLEYHLGQGK
VLQDAFLHALKERGAPAIFTATTMSVGVGTWIFSALKLQSDMGLLLTFMFFINMLGAVLL
LPALMAWLSGWRKPPATVTVHA