Protein Info for LRK53_RS09880 in Rhodanobacter sp000427505 FW510-R12

Annotation: chromosome segregation protein SMC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1169 PF13175: AAA_15" amino acids 1 to 172 (172 residues), 33.2 bits, see alignment E=1.1e-11 TIGR02168: chromosome segregation protein SMC" amino acids 2 to 1159 (1158 residues), 1026.9 bits, see alignment E=0 PF02463: SMC_N" amino acids 3 to 1152 (1150 residues), 218.4 bits, see alignment E=2.1e-68 PF13476: AAA_23" amino acids 6 to 231 (226 residues), 66.6 bits, see alignment E=1.3e-21 PF13304: AAA_21" amino acids 27 to 164 (138 residues), 31.7 bits, see alignment E=4.5e-11 PF06470: SMC_hinge" amino acids 526 to 616 (91 residues), 30.5 bits, see alignment 1.1e-10

Best Hits

KEGG orthology group: K03529, chromosome segregation protein (inferred from 59% identity to psu:Psesu_1738)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1169 amino acids)

>LRK53_RS09880 chromosome segregation protein SMC (Rhodanobacter sp000427505 FW510-R12)
MRLTTIKLAGFKSFVDPTTLHLPSNMIGVVGPNGCGKSNIIDAIRWVMGESAASRLRGDS
LTDVIFSGSNTRKPVGQATVELIFDNADGSIQGEYGQYAEISVKRQVTRDGQSAYFLNGA
RCRRRDITDLFLGTGLGPRSYSIIEQGMISQIIEAHPEELRTHLEEAAGISKYKERRKET
ESRIKATRENLDRVKDVRDEVDKQLEHLHRQARAAERWKALKEEQTRKEAELRALEYRGL
KSQHDGEGEVLSAAEIEIEKQLAGQRQIEAQLESVRERHTDASEHLNAVQAEVYKVGAEI
ARVEQQVRYNKETAERLQRAHGDAEREHAELAAHIATDRDQVEALRLALAEGEPKLEALQ
QLQDDTAEAQRSTEAKLADWQQRWDSHTRNAGESNRAAEVERTKLNYLDRQAIDLSRRRE
ALEAEQKATDVAALDAAGQQLVDEHETQRERVETLGSLLDQHKGGHEKLLEEERQVQSAL
NEARQQLQAARGRQASLEALQHAALGQEENAASGWLARLGLNKSRRLGESLQVENGWETA
VETALSGFLDSVLVDGSHALAAEFEALENADVALLDAADGGAHTAGTLAAHVRGPAAALT
ILGHVLTAESLGDAHQQVASLSALAPYQSVITRSGEWLGPGWARVRRAQGSQVGVLARER
ELRLLAEQIAALEAQLETSSERLDALRISKFEAERARDDAQRELYNAHRRQSELAGQLQS
HRGKLETARARAEKVSGELDGLAAQLDELQGQTREARARLDESVGLMGDQEDQRRELENE
RRTLLEAREEARMNAREAAEQSHALALALESKRSSLGSLEQALGRMDAQLRQIEARRDEI
SEQLAAGSDPIAELEAERQAYLDQRLLVDKQLVEARRALEDCDLEFRKLEQQRHLAEQGL
ASLREGLSEKRLAAQALQLRAEQLAAAINASGLELETLLTELAADIDAEQWRAQLGDLGQ
KIARLEPVNLAAIQEHAEQSERKTYLDNQLADLTSAMETLENAIKKIDRETRQRFKETFD
KVNAGVQELFPRLFGGGHAYLELTGDDLLNTGVSIMARPPGKRPSNISLLSGGEKALTAV
SLVFAIFNLNPAPFCLLDEVDAPLDEANVGRFSNMVREMSEKVQFIFVSHNKATMEAASQ
LCGVTMREPGVSRLVQVDLAEAAKLAGAA