Protein Info for LRK53_RS09835 in Rhodanobacter sp000427505 FW510-R12

Annotation: DHHA1 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 transmembrane" amino acids 201 to 219 (19 residues), see Phobius details PF01368: DHH" amino acids 74 to 243 (170 residues), 75.8 bits, see alignment E=5.6e-25 PF02272: DHHA1" amino acids 365 to 482 (118 residues), 50.3 bits, see alignment E=4.4e-17 PF17768: RecJ_OB" amino acids 496 to 598 (103 residues), 71.2 bits, see alignment E=1.1e-23

Best Hits

Predicted SEED Role

"Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-)" in subsystem DNA-replication or DNA Repair Base Excision or DNA repair, bacterial RecFOR pathway (EC 3.1.-.-)

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (602 amino acids)

>LRK53_RS09835 DHHA1 domain-containing protein (Rhodanobacter sp000427505 FW510-R12)
MSVLQLRRRESKGAPRGWPDSVHPVLQRIYAARGVLEPGQAEHRLARMLSPQLLGGMAQA
VELLVEAIRDDWAILIAGDYDCDGATGTAVAVRGLRLLGARRVDYAIPNRFAHGYGLSPA
FVASLQPTPQLIVTVDNGVASVAGVAAAQARGIKVIVTDHHLPGEQLPACDALVNPNVGP
EKCGQGSPLFDSRVQDARMKNLAGVGVMFYLLLALRAKLHGQGAFGAAKPDLSPLLDLVA
LGTVADLVPLDFNNRVLVEAGLQRMRSGRACAGIAALVEVGKRSLATLCSTDLAFTVGPR
LNAAGRLEDMRLGVACLLTDDAAQARRHAEQLDAINRERRDLQASMVAEAELMAASLGHT
DAVGVALFEPSWHAGVVGLVASKLKERLHRPVIAFAPAGIEECGEGSPPFDSGAQEVRTG
NTQLRGSARSIPGFHIRDALAAIDARQPGLIERFGGHAMAAGLSLKADDYPRFAAAFDAI
ARELIEPERLQAVLYTDGELPPGAATLALARQLREAGPWGQAFPEPLFDNLFDCAGWKLM
GERHLRLQLRDPRDGAVHDAVMFNAYHGQPPPPRLRAAYELTINDWQGRESPRLLLRHIE
PA