Protein Info for LRK53_RS09395 in Rhodanobacter sp000427505 FW510-R12

Annotation: PAS-domain containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1102 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 37 to 54 (18 residues), see Phobius details amino acids 66 to 85 (20 residues), see Phobius details amino acids 114 to 133 (20 residues), see Phobius details amino acids 158 to 175 (18 residues), see Phobius details amino acids 187 to 213 (27 residues), see Phobius details amino acids 230 to 252 (23 residues), see Phobius details amino acids 265 to 285 (21 residues), see Phobius details amino acids 314 to 344 (31 residues), see Phobius details amino acids 368 to 385 (18 residues), see Phobius details amino acids 397 to 417 (21 residues), see Phobius details amino acids 426 to 449 (24 residues), see Phobius details amino acids 477 to 496 (20 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 598 to 720 (123 residues), 26.2 bits, see alignment E=3.7e-10 PF13188: PAS_8" amino acids 600 to 645 (46 residues), 21.2 bits, see alignment (E = 6.6e-08) PF00989: PAS" amino acids 600 to 698 (99 residues), 32.5 bits, see alignment E=2.3e-11 PF08448: PAS_4" amino acids 604 to 715 (112 residues), 27.6 bits, see alignment E=8.9e-10 PF12860: PAS_7" amino acids 604 to 717 (114 residues), 147.6 bits, see alignment E=4.9e-47 PF02518: HATPase_c" amino acids 858 to 964 (107 residues), 79.2 bits, see alignment E=9.9e-26 PF00072: Response_reg" amino acids 986 to 1092 (107 residues), 43.5 bits, see alignment E=9.7e-15

Best Hits

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1102 amino acids)

>LRK53_RS09395 PAS-domain containing protein (Rhodanobacter sp000427505 FW510-R12)
MLSASVIAIAALCWLGLLFGVALLGERRPHIFEKRWAIVYALSLAIHCTSWTFYGTVTQA
SRSGWWLPPTFVGAILMYLFALGFLRRMVQLVREYNAGSLADLIAVRLGRHPGLAALVTV
VVVIGIVPYIALQLKAVAMSYGILSHGQLAESSPWQDSALYVALLMALFAMLFGTRRAST
MAHNRGLVLAMAFESLFKLGAMLALGTLLFAALPADLPANVPAPPDSSGFPALILLGALA
MFTMPHQFYAGIVECREDGQLRTARWLFPLYLLLISLPILPLARLGDAWLGASGVSSDMY
VLALPLARGEHGLALVAFLGGLSAATSMVVIATLTLSLMVVNHFVAPLRVRAGWGRDEHG
DLRGELLNYRRVAILVVILLAWAYSRLLAGNEALADIGAISFSALAGLTPALLAAVYRPQ
LGSRAVMAGLAAGTLVWLYAVLPALLSSMPAWLHDGPFGLHWLAPDGLLGLGNWNRLGRA
VVVSLLLNVAVMLAMAGSRYGRVARTVSVGDVGLVELRALAARFLPPERVEYLFASAPAA
GPAGSARVAEVEHELAAVIGAASARLLLEVVHRQGRDDLDTVVAIVGEAAQDLRFNQRVL
EAALENMSQGICVVDAELRLVAWNTPYARLFDYPPEMLQVGRPVAELTRHNIDIGMLGPG
EVEQRVQRRLAHMREGTRHLSERRFPDGTIVEIRGNPMPGGGFVATFTDVTAFRQAEAAL
KRINETLELRVEARTRELAAASAEAQAANEAKSRFLAAVTHDLMQPLHAAQLFAHALTER
GGDAANARHLNGALAATEGLLTGLLDVARLEGGRLHPQPRAFALAEVLDPLAAEFRAIAI
DRGVRLDVVGTRAWVRSDPQLLRRVLQNFLSNALRYGERGRVLLGTRRRGGQLRIEVWDT
GPGIAPEEQRLIFQEFRRGSAAGGQGLGLGLSIAQRMADLLGHPLGLRSWPGRGSVFHVD
APVAQAVARSAPPAHAQQPLPAGRALLLDNEPAALAALGSLLAGWGWHVHVARNAEQALA
APWRPDLHILDFHLDGGQTGLDVWHLLRARYADVPTVMLTADRDGELRQRLLEAGVGVLY
KPLKPLALRQVLQRVIAGAERA