Protein Info for LRK53_RS08855 in Rhodanobacter sp000427505 FW510-R12

Annotation: Maf family nucleotide pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 192 TIGR00172: septum formation protein Maf" amino acids 3 to 185 (183 residues), 159 bits, see alignment E=4.7e-51 PF02545: Maf" amino acids 4 to 186 (183 residues), 178.3 bits, see alignment E=6.9e-57

Best Hits

Swiss-Prot: 58% identical to NTPPB_BURMA: 7-methyl-GTP pyrophosphatase (BMA0526) from Burkholderia mallei (strain ATCC 23344)

KEGG orthology group: K06287, septum formation protein (inferred from 66% identity to sml:Smlt1023)

MetaCyc: 52% identical to m7GTP pyrophosphatase (Escherichia coli K-12 substr. MG1655)
RXN0-7079

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (192 amino acids)

>LRK53_RS08855 Maf family nucleotide pyrophosphatase (Rhodanobacter sp000427505 FW510-R12)
MPCIVLGSTSRYRAELLRRLLPDFEQAAPGTDETPQPDEPPAARALRLAIAKAEAVAREH
PGALVIGSDQVAELDGLILDKPGNAERARAQLAASSGREVHFHTALCLLDTRNGRRHTHV
DHTRVRFRELDAAEIARYVEREQPLDCAGSFKCEGLGISLFEAIDNCDPSALIGLPLIAL
ARLLREAGVELP