Protein Info for LRK53_RS07925 in Rhodanobacter sp000427505 FW510-R12

Annotation: metalloregulator ArsR/SmtB family transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details PF12840: HTH_20" amino acids 13 to 61 (49 residues), 43.4 bits, see alignment 1.6e-14 PF13412: HTH_24" amino acids 15 to 60 (46 residues), 26.9 bits, see alignment 1.8e-09 PF01022: HTH_5" amino acids 15 to 60 (46 residues), 58.9 bits, see alignment 2.2e-19 PF12802: MarR_2" amino acids 16 to 62 (47 residues), 35.9 bits, see alignment 4.1e-12 PF01209: Ubie_methyltran" amino acids 132 to 253 (122 residues), 34.1 bits, see alignment E=1.1e-11 PF13489: Methyltransf_23" amino acids 137 to 285 (149 residues), 54.9 bits, see alignment E=5.5e-18 PF05175: MTS" amino acids 141 to 250 (110 residues), 27.5 bits, see alignment E=1.4e-09 PF13847: Methyltransf_31" amino acids 149 to 248 (100 residues), 53.8 bits, see alignment E=1.1e-17 PF13649: Methyltransf_25" amino acids 150 to 241 (92 residues), 68.8 bits, see alignment E=3.3e-22 PF08242: Methyltransf_12" amino acids 151 to 243 (93 residues), 58.3 bits, see alignment E=6.3e-19 PF08241: Methyltransf_11" amino acids 151 to 244 (94 residues), 72.3 bits, see alignment E=2.5e-23

Best Hits

KEGG orthology group: K03892, ArsR family transcriptional regulator (inferred from 64% identity to xom:XOO_1956)

Predicted SEED Role

"Transcriptional regulator, ArsR family / Methyltransferase fusion"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (309 amino acids)

>LRK53_RS07925 metalloregulator ArsR/SmtB family transcription factor (Rhodanobacter sp000427505 FW510-R12)
MDLATASSVLRLLADPTRVRLLALLEREELTVAELAAVLHLAQPRVSTHLAKLKEAGLVR
DRRAGVSAYYRANNEGDAAQHDLLASLRASIDDALLREDAARLPGVLANRAREEGWADTV
AGDMERHYSPGRTWETLARSLLQLLETGDVLDIASGDGITAELLAPHAHSIVCVDSSERV
VEAAAKRLKAFANVRVVRGDMHALELGQQRFDLVLMLHALTYAERPAKAVAEAARLLRPG
GRLLAVTLGQHDHRAAVEPFDHRNLGFSGEQLDGYARAAGLDVLSCNRLSRERKAPHFEV
ISLLARKRA