Protein Info for LRK53_RS07705 in Rhodanobacter sp000427505 FW510-R12

Annotation: ferrous iron transporter B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 611 transmembrane" amino acids 221 to 242 (22 residues), see Phobius details amino acids 248 to 265 (18 residues), see Phobius details amino acids 276 to 299 (24 residues), see Phobius details amino acids 320 to 343 (24 residues), see Phobius details amino acids 355 to 381 (27 residues), see Phobius details amino acids 393 to 414 (22 residues), see Phobius details amino acids 456 to 475 (20 residues), see Phobius details amino acids 490 to 507 (18 residues), see Phobius details amino acids 514 to 535 (22 residues), see Phobius details amino acids 542 to 565 (24 residues), see Phobius details amino acids 585 to 606 (22 residues), see Phobius details PF01926: MMR_HSR1" amino acids 7 to 124 (118 residues), 62.3 bits, see alignment E=9.2e-21 PF02421: FeoB_N" amino acids 7 to 166 (160 residues), 171 bits, see alignment E=2.7e-54 PF07670: Gate" amino acids 284 to 380 (97 residues), 75.5 bits, see alignment E=8.3e-25 amino acids 455 to 581 (127 residues), 50.6 bits, see alignment E=4.9e-17 PF07664: FeoB_C" amino acids 397 to 449 (53 residues), 55 bits, see alignment 1.1e-18

Best Hits

KEGG orthology group: K04759, ferrous iron transport protein B (inferred from 73% identity to bgl:bglu_1g10740)

Predicted SEED Role

"Ferrous iron transport protein B" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (611 amino acids)

>LRK53_RS07705 ferrous iron transporter B (Rhodanobacter sp000427505 FW510-R12)
MSASTLRIALVGNPNCGKTALFNLLTGGRQKVANYAGVTVERKEGRFTAPSGRVLQILDL
PGAYSFDASSPDEQITRDVCAGNYPGEAPPDLIVCVADATNLRLHLRFVLEVKRLGRPVV
LALNMMDTARSRGIVIDVPELSRRLGLPVVETVAVKRGGARALIERVDGEVPPAAPVQSD
DAADHADLHAQVRELLAATVRMPRVTAELDDALDRWTLHPVFGLAILALVMFLVFQAVYA
AGKPMSDLIGGGFGWLGGHVAALMPDGPLRSLVVDGLFGGVGTVLGFLPVILVLFFFILT
LEESGYLPRAAFLLDRLMLSVGLTGRSFIPLLSSFACAIPGIMGTRSITDPRDRLATILI
APLMTCSARLPVYALLIGAFIPARKVFGLFNLQGVVLFALYLAGILGAMLVGWVMKHLRR
DKSEHALLMELPSYRLPKVRDVAIGLYERGMIFLKRLTGVILGLTVLMWFLSTFPGAPEG
ATLPAIDYSFAGYIGRGLQYVFAPIGFNWQISLALIPAFAARETAVAALATVYLVGGEAE
GLGQALVGQIPLASALSLLVWFAYAPQCMSTLAIIKRETDSWRNVAISFGYMFVMAYTAS
FIVYQVTRTLT