Protein Info for LRK53_RS07190 in Rhodanobacter sp000427505 FW510-R12

Annotation: PepSY domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 138 to 162 (25 residues), see Phobius details amino acids 187 to 216 (30 residues), see Phobius details amino acids 345 to 366 (22 residues), see Phobius details amino acids 387 to 409 (23 residues), see Phobius details amino acids 419 to 437 (19 residues), see Phobius details amino acids 447 to 470 (24 residues), see Phobius details amino acids 477 to 498 (22 residues), see Phobius details PF03929: PepSY_TM" amino acids 13 to 367 (355 residues), 178.4 bits, see alignment E=1.5e-56

Best Hits

KEGG orthology group: None (inferred from 65% identity to smt:Smal_2808)

Predicted SEED Role

"putative iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (522 amino acids)

>LRK53_RS07190 PepSY domain-containing protein (Rhodanobacter sp000427505 FW510-R12)
MKLKPATLRTFTTLHSWMGMVAGFALFVAFYAGAITVFHRGLQQWSTPQAVDAAPATLDD
AQRLLDGVLARHPQAREHLGMTFPGYELAQPTAYWLDAHGTWQFATPDHLAGSPTPPGAS
LPELINELHYTLGLPLVGTWLMGLVSLLYGVALVSGFVIHLPRLAKDLFALRPGRNLKRF
WQDAHNVIGVLSLPFHIMFAVTGALLCLLFVLMLALNPLIYDSKLMAASPAAMDTAPIVQ
KADIARPLSPLASWHARSIEVAREHGVADFEPGYLKLAHAGDAHAVVEVTGRSSHGLGSG
AVALAAVDGSMLATQLPGARDANHATLAAVYALHFGDYGNVVVQWLYFLLGLGGAFLFYS
GNLLWIESRRKRRQTEQGRTSLAMARATVGICIGVCVAVSAAFVAAQLLPWLGWNSATGE
RWVCFASWALCVLWASWRAPLRAARELLWLAAIVTALVPLAHGLATGWWFWRSAAVGHGA
LLAIDLGALALAAGFAALARATSRRGRDGATNSVWAISAPQP