Protein Info for LRK53_RS06945 in Rhodanobacter sp000427505 FW510-R12
Annotation: beta-ketoacyl-[acyl-carrier-protein] synthase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 53% identical to NODE_RHILV: Nodulation protein E (nodE) from Rhizobium leguminosarum bv. viciae
KEGG orthology group: K14660, nodulation protein E [EC: 2.3.1.-] (inferred from 67% identity to xal:XALc_1783)MetaCyc: 37% identical to 3-oxoacyl-[acyl-carrier-protein] synthase subunit (Arabidopsis thaliana col)
Beta-ketoacyl-acyl-carrier-protein synthase II. [EC: 2.3.1.179, 2.3.1.41]; 2.3.1.179,2.3.1.41 [EC: 2.3.1.179, 2.3.1.41]; 2.3.1.179,2.3.1.41 [EC: 2.3.1.179, 2.3.1.41]; 2.3.1.179,2.3.1.41 [EC: 2.3.1.179, 2.3.1.41]; 2.3.1.179,2.3.1.41 [EC: 2.3.1.179, 2.3.1.41]; 2.3.1.179,2.3.1.41 [EC: 2.3.1.179, 2.3.1.41]; 2.3.1.179,2.3.1.41 [EC: 2.3.1.179, 2.3.1.41]
Predicted SEED Role
"3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179)" (EC 2.3.1.179)
MetaCyc Pathways
- superpathway of fatty acids biosynthesis (E. coli) (49/53 steps found)
- superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
- palmitate biosynthesis II (type II fatty acid synthase) (29/31 steps found)
- superpathway of unsaturated fatty acids biosynthesis (E. coli) (18/20 steps found)
- biotin biosynthesis I (14/15 steps found)
- oleate biosynthesis IV (anaerobic) (13/14 steps found)
- superpathway of fatty acid biosynthesis I (E. coli) (14/16 steps found)
- 8-amino-7-oxononanoate biosynthesis I (10/11 steps found)
- (5Z)-dodecenoate biosynthesis I (6/6 steps found)
- palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) (8/9 steps found)
- gondoate biosynthesis (anaerobic) (4/4 steps found)
- (5Z)-dodecenoate biosynthesis II (5/6 steps found)
- stearate biosynthesis II (bacteria and plants) (5/6 steps found)
- cis-vaccenate biosynthesis (4/5 steps found)
- fatty acid elongation -- saturated (4/5 steps found)
- superpathway of fatty acid biosynthesis initiation (4/5 steps found)
- octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) (9/12 steps found)
- palmitate biosynthesis III (21/29 steps found)
- stearate biosynthesis IV (4/6 steps found)
- anteiso-branched-chain fatty acid biosynthesis (24/34 steps found)
- even iso-branched-chain fatty acid biosynthesis (24/34 steps found)
- odd iso-branched-chain fatty acid biosynthesis (24/34 steps found)
- fatty acid biosynthesis initiation (mitochondria) (2/4 steps found)
- tetradecanoate biosynthesis (mitochondria) (17/25 steps found)
- petroselinate biosynthesis (2/6 steps found)
- streptorubin B biosynthesis (20/34 steps found)
- mycolate biosynthesis (20/205 steps found)
- superpathway of mycolate biosynthesis (21/239 steps found)
KEGG Metabolic Maps
- 1- and 2-Methylnaphthalene degradation
- Alkaloid biosynthesis I
- Alkaloid biosynthesis II
- Anthocyanin biosynthesis
- Benzoate degradation via CoA ligation
- Biosynthesis of terpenoids and steroids
- Biosynthesis of type II polyketide backbone
- Biosynthesis of unsaturated fatty acids
- Butanoate metabolism
- Carotenoid biosynthesis - General
- Diterpenoid biosynthesis
- Ether lipid metabolism
- Ethylbenzene degradation
- Fatty acid biosynthesis
- Glycerophospholipid metabolism
- Glycosphingolipid biosynthesis - ganglio series
- Histidine metabolism
- Limonene and pinene degradation
- Lipopolysaccharide biosynthesis
- Lysine degradation
- Phenylalanine metabolism
- Tyrosine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.3.1.-, 2.3.1.179, 2.3.1.41
Use Curated BLAST to search for 2.3.1.- or 2.3.1.179 or 2.3.1.41
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (410 amino acids)
>LRK53_RS06945 beta-ketoacyl-[acyl-carrier-protein] synthase family protein (Rhodanobacter sp000427505 FW510-R12) MPIVSTRRVVITGMGAISPLGVGAAALWQGLREGRSAIGPLRHVDAGRLRVKVAAQVPES FDPAAHIDERTLPLLDRTSEFALHAAREAVVQSGVDFAGDGLGQRTAVIVGTGVGGETTQ DEQSRRLYAENTPRAHPLTIVRLMTNASASQISIAYGLHGPTYAVASACASANHAIIQAA QMIRYGMADAAVTGGTEACLTYGALRAWEAMRVLADDTCRPFSANRRGLVLGEGAGIFVL ESLEHAQARGATILAELAGTGMSADASDIVMPSAEGAAAAMQQALQEAELNPGDVDYINA HGTGTQANDVTETRAIRLAFGAQADRLAVSSTKSMHGHALGASGALELVAAIGALRENVV PPTANLDKVDPACDLDYVPNVAREMPVRVVLSNSFAFGGLNAVLALKRAP