Protein Info for LRK53_RS06800 in Rhodanobacter sp000427505 FW510-R12

Annotation: FAD-binding oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 PF01565: FAD_binding_4" amino acids 40 to 178 (139 residues), 139.5 bits, see alignment E=6.1e-45 PF02913: FAD-oxidase_C" amino acids 217 to 459 (243 residues), 186.8 bits, see alignment E=6e-59

Best Hits

KEGG orthology group: None (inferred from 75% identity to xal:XALc_1327)

Predicted SEED Role

"D-2-hydroxyglutarate dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>LRK53_RS06800 FAD-binding oxidoreductase (Rhodanobacter sp000427505 FW510-R12)
MSDPRLAELSRRLPELRVLNAPAELEHYGRDWTRRWTPAPLAIALPTSTEEVQAIVRWAN
ESRVAIVPSGGRTGLSGGAVAANGELVLSLERMNRVLDFDAVDCTLTVQSGMILQHVHEA
AREHGLVYPVDFAARGSCSIGGNIATNAGGIRVIRYGNTREWIAGLKVVAGNGELLELNR
GLIKNSSGYDFRQLLVGSEGTLGIVAEATLKLTEPPPPSQVMLLALPDMDALMQVFALFR
ARLVLQAFEFFTDHALRHVLAHGAQRAIDGDHPYYVVTEFDAADERQQEAALAAFEQGMA
EGWISDGVIAQSEAQAAALWRLREGITESLAPRRPYKNDVSVRISAVPAFLHEMQALLAR
EYPQAEVVWFGHIGDGNLHINVLRPDGLVEDAFIAQCEHVTALLAATLQRHGGSISAEHG
IGLVKRAYLESTRSATEIALMRGVRRVFDPNGVLNPGKLFAPD