Protein Info for LRK53_RS06360 in Rhodanobacter sp000427505 FW510-R12

Annotation: elongation factor Tu

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 TIGR00485: translation elongation factor Tu" amino acids 1 to 396 (396 residues), 756.4 bits, see alignment E=5.2e-232 PF00009: GTP_EFTU" amino acids 10 to 203 (194 residues), 213.5 bits, see alignment E=3.1e-67 TIGR00231: small GTP-binding protein domain" amino acids 13 to 149 (137 residues), 51.5 bits, see alignment E=9.7e-18 PF03144: GTP_EFTU_D2" amino acids 227 to 296 (70 residues), 76.8 bits, see alignment E=2.1e-25 PF03143: GTP_EFTU_D3" amino acids 300 to 394 (95 residues), 136.2 bits, see alignment E=7.8e-44

Best Hits

Swiss-Prot: 92% identical to EFTU_XANC5: Elongation factor Tu (tuf1) from Xanthomonas campestris pv. vesicatoria (strain 85-10)

KEGG orthology group: K02358, elongation factor Tu (inferred from 92% identity to psu:Psesu_2337)

Predicted SEED Role

"Translation elongation factor Tu" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (396 amino acids)

>LRK53_RS06360 elongation factor Tu (Rhodanobacter sp000427505 FW510-R12)
MAKGKFERTKPHVNVGTIGHVDHGKTTLTAALTKVGAERFGGEFKDYSAIDAAPEEKARG
ITISTAHVEYESPKRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHI
LLSRQVGVPYIVVFLNKADMVDDAELLELVEMEVRELLSKYDFPGDDTPIIHGSALKALE
GDQSEIGVPAIIKLVDALDSYIPEPVRAIDKPFLMPVEDVFSISGRGTVVTGRIERGVIK
VGDEIEVVGIRDTQKTTVTGVEMFRKLLDQGQAGDNAGLLLRGLKRDDVERGQVLAKPGT
ITPHTDFEAEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGAVTLPEGVEMVMPGDNVK
MVVSLIHPIAMDEGLRFAIREGGRTVGAGVVAKVIK