Protein Info for LRK53_RS05985 in Rhodanobacter sp000427505 FW510-R12

Annotation: class I SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 PF13489: Methyltransf_23" amino acids 135 to 275 (141 residues), 100.4 bits, see alignment E=3.2e-32 PF08003: Methyltransf_9" amino acids 135 to 278 (144 residues), 33.3 bits, see alignment E=9.1e-12 PF13847: Methyltransf_31" amino acids 139 to 235 (97 residues), 33.8 bits, see alignment E=9.1e-12 PF07021: MetW" amino acids 139 to 242 (104 residues), 34.5 bits, see alignment E=5.8e-12 PF13649: Methyltransf_25" amino acids 142 to 226 (85 residues), 42 bits, see alignment E=4.5e-14 PF08241: Methyltransf_11" amino acids 142 to 229 (88 residues), 51.3 bits, see alignment E=5.3e-17 PF08242: Methyltransf_12" amino acids 142 to 227 (86 residues), 47.9 bits, see alignment E=6.6e-16

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (333 amino acids)

>LRK53_RS05985 class I SAM-dependent methyltransferase (Rhodanobacter sp000427505 FW510-R12)
MASEWRIDELQTVATCPACGAAPGEYRYQQLHDYLESVPGEWSLRDCRGCGSLFLDPRPT
PQAIGKAYASYYTHRSGATTYEDDNGHSLLWRLANGYMNARYGPQRLPAIAAGRFMIPLI
PALRQQLDFFYRGLPRVKGRLLDVGCGNGVFLLRARAAGWNVAGVEPDPLAVATARLDGL
DVFEGTLDSFCDAQRFDVITSSHVIEHVHEPRALLKRMFDLLRTDGTIWLATPNVQSMGH
RWFGRAWRGLEPPRHLVVFSAQALRGLLTKVGFTDIRFHRRGRGAAYILRASRELARRKR
SDARGLPPGVVDLMASLSATAGEELVITARKPC