Protein Info for LRK53_RS05750 in Rhodanobacter sp000427505 FW510-R12

Annotation: Hpt domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 200 400 600 800 1000 1200 1400 1600 1800 2032 transmembrane" amino acids 1853 to 1875 (23 residues), see Phobius details PF26379: FimL_2nd" amino acids 163 to 305 (143 residues), 124 bits, see alignment 1.7e-39 PF27543: FimL_C" amino acids 444 to 560 (117 residues), 119.1 bits, see alignment 3.7e-38 PF01627: Hpt" amino acids 689 to 781 (93 residues), 47 bits, see alignment 8.8e-16 amino acids 877 to 964 (88 residues), 40.7 bits, see alignment (E = 8.3e-14) amino acids 1249 to 1341 (93 residues), 51.1 bits, see alignment 4.5e-17 PF02518: HATPase_c" amino acids 1605 to 1740 (136 residues), 62.6 bits, see alignment 1.6e-20 PF01584: CheW" amino acids 1745 to 1877 (133 residues), 73.1 bits, see alignment 6.3e-24 PF00072: Response_reg" amino acids 1907 to 2017 (111 residues), 98.6 bits, see alignment 8.6e-32

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (2032 amino acids)

>LRK53_RS05750 Hpt domain-containing protein (Rhodanobacter sp000427505 FW510-R12)
MRLQDHIDFTTLQWVKPELDDTLSIAREALESYVDNPGKRDYMRTCVDHLHQVQGTLQMV
ELYGAATVTAEMEALALALLADKVTYREEAYAALMRGLMQLPDYLERLSSGHRDVPVVLL
PLLNDLRASRELEPLPESAMFHPNLDAFLPEQAPAAMSEAYAEAHRGELVELRLRFQQQL
LGWFRGQNVAQQLVNMRKTLLAITARCHQVHGRRLWWIAAGVLEGLEQGVLKGQAGEIRQ
LIGKVDRNIRLLIEQGEASLRGGDADDVARKLLYIVAQAKQRSPQMELLRDIYALDTLLP
DAGELEHARGSMAGHNRALLDSVSRALKDDLLRVKEALDLFLRQQNGDPAQLAAQGEVLE
RVGDTLGMLALSVPRRVVAEQRRVLDEIANRMRQADEETLLDVAGALLYVEASLDDHIES
LGSEDEAGTSQVMPSLPRSEALGVVTTLMQEAIANTGKVKDAIVAFVESGWEHGRLAGAP
ELMDEVAGAMHMLSSPRPAELAQGVGRFIGNELLDDRRVPSGAQMDQLADALAALEYYLE
AAREHRGGLEHILDVAEHSLSLLGYWPLLSARVASAAPLASEAAPVASAAVDGEHLELSE
SVSLLPGEDLRQLFVGDSQPLAAAVHDLDGLRLAQTETATPAGADRAAADEAGEDWIEIE
EEVVEQVPVRDALADNTNFNVNAEGIDDDIREIFLEEMQEEIDNLRSAEQLWLADPAQSA
ALVGIRRSFHTLKGSGRLVGAGVLGEFAWKVEDMLNRVLDGTIQPDENVQALVRHAIDAL
PQLLAALKGEGMPRAPLGAIMHTAEQLAAGNPAWVEDHAPRAMETVRRIVRRRVPRLDAA
AESIPTAGLAGVGAAPEPIEPEHAVEMPVMPPVDPVLLEILRSEVAQYLQTIRAAIQRSD
DELPIGEELLRAVHTLHGAIAMVDIPLLTQLLSPLEGLFKRLRAANLPLSSEGLRLLGQA
VDVVDRVMSQFDAAEPQLPDADALTAQIASLRDRYPESKVAHVVFEPQADEADEAKSAES
AGATDEADEADEAEAYQAIIADSLAAGMADAAAARAGTAPADAPANAGEIPQVHLEDAQH
AELTAELVAALGAFEPERADAERAAAEKLAAEQAAAARAEAEKLAAEQAATAQAEAEKLA
AEQAATAQAEAEKLAAEQAAAAQVEAEKLAAEQAAAAQAEAEKLAAEQAAAAQAAAEKLA
IEQAAAAQAAAEKQAAEQAAAGRTSEEATGTVTPEPAHALAGSGQIDADLMEVFIDEARE
ILDHADDVLAQWHAEPAELVHVPELQRDLHTLKGGARIAGLTAVGDLSHAIETLLEEPIR
DVSRTGPLIAALEASFDQLHALVQRVAQGQATEYPRAMIDHLLELAGETVLADDATAAMP
APASVPTASSPAVSAAGEPGLPELMPEAEEEVRSPQEQIRVRADLLDNLVNHAGEVAIYR
SRLEQQVAGYRFNLVELEQTVARLRSQLRMLEIETEAQIIARFQREHREAGMAAFDPLEL
DRYSQLQQYSRALAESVSDLVSIQSMLDELTRQAETLLIQQSRVSTELQDGLLRTRMLPF
DTMVPNLRRTLRQAAQEQDKHAQLHVDGAHGEMDRNLLDRIKAPFEHMLRNAIAHGIETP
AERRKAGKPVEGVVSITVAREATEVVIRVSDDGRGLNREAIRKRGIERGLLRPETRPTDN
QLLSLITQTGFSTASQVTQLAGRGVGMDVVANEIKQLGGSLSIESEEGKGTTFILRLPFT
LAVTQAILVRIGEATFAIPITSVQGVARVNPDELTALMAEAEPSFQYGLEDYGIHDLAEL
LGLPPGLPTEDEQQPLLLTRAGDLRAAIRIDAVLGSREIVVKSVGPQISSVPGLLGATIM
GDGSVLIILDLAPLVRHGMIRREQRLAEGLSAVQAPVVEEVQTKPLVMVVDDSITMRKVT
SRVLERHEYEVSTAKDGVDALEKLHERVPDLMLLDIEMPRMDGYELATHMKADPRLRDVP
IIMITSRSGDKHRQRALDIGVDRYLGKPYQEAELLVQIGEVLEQRAVEPVHD