Protein Info for LRK53_RS04615 in Rhodanobacter sp000427505 FW510-R12

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 946 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 204 to 226 (23 residues), see Phobius details PF05227: CHASE3" amino acids 50 to 194 (145 residues), 64.9 bits, see alignment E=2.6e-21 PF00672: HAMP" amino acids 225 to 271 (47 residues), 28 bits, see alignment 7.6e-10 PF13185: GAF_2" amino acids 299 to 431 (133 residues), 49.6 bits, see alignment E=1.7e-16 PF01590: GAF" amino acids 305 to 417 (113 residues), 23.1 bits, see alignment E=3.4e-08 PF00512: HisKA" amino acids 548 to 615 (68 residues), 61.8 bits, see alignment 1.8e-20 PF02518: HATPase_c" amino acids 663 to 784 (122 residues), 91.5 bits, see alignment E=1.8e-29 PF00072: Response_reg" amino acids 828 to 937 (110 residues), 95.5 bits, see alignment E=8e-31

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (946 amino acids)

>LRK53_RS04615 response regulator (Rhodanobacter sp000427505 FW510-R12)
MPVNRTPNTWLANQPLQHKIMLAIGLLLGLFLLANALTLHSLRQQEDDRGWATHTYQVLL
QLDHVLQSMQASQVGARGYLLTQDAAQRYAFESANRDLGTDLARLRGLMSDSPLQLSRID
KVEETAQLWQREFRSGVIDALAGLGTLDPAQAALQRQRIQSDYLKHRSISAKEIEDVIAQ
MTLDEEALLSTRNQRLDRTIAITRTVDIVAAVLAILFGLAVIRLTLRLVTRPLRALTNQL
TRLANHDHDFEIRRLERRDEIGEIARALQVFKQMSVDNQTQSWIKEQVSDVAHLLLQATT
HKEFAQWLTSALVPLCKAGVSLFYSYDDARQRLDLIGSYGLRLSNRSADQYLPGEGLVGQ
CALERKPIILDDVPADYLHIDSGSGAALPGHLVILPVLYRDTLIGVLELAGFTPPSPVVH
QLLDELLPLVALSLENLNRTVSVQGLLLRTQEQADELRVSELVMRQQKEVLRDNNDALQA
KTEELEEQSRRLIASEEELRIQADELQASNEELREMTESLNRQKYVLEDLQQETADKAAE
LARASQYKSEFLANMSHELRTPLNSLLILSRDLAGNAGGNLDADQVESARIIHDAGNSLL
HLINDILDLSKIEAGKMELVIDELPLAELAQRLRRTFGHVAAQKSLAFALTIGPDLPAAL
RTDGARLEQIANNLLGNAFKFTTEGAVSVHVGRPDGEVDIPELLHGQPLLALTVSDTGIG
IPADKLERIFNAFEQVDAGTSRQFGGTGLGLAISRRMARMLGGDLVVRSEPGHGSRFTAL
LPEEPPAAASMQSQAMSEQQATAPFTAVVTTPDLPAAAAGGELAGRRVLLVDDDMRNLFA
LSRVLRGWGMQVSLAQDGAKALRMLAEEAAPELLLIDIMMPGMDGYEMIRTIRAQPHYGA
LPIIALTAKAMHGDREKCLQMGASDYLSKPLDLDRLAVTLLAWLRR