Protein Info for LRK53_RS03855 in Rhodanobacter sp000427505 FW510-R12

Annotation: ATP-dependent DNA helicase DinG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 705 PF00270: DEAD" amino acids 44 to 93 (50 residues), 24.1 bits, see alignment 4e-09 PF13307: Helicase_C_2" amino acids 542 to 696 (155 residues), 124.9 bits, see alignment E=5.5e-40

Best Hits

Predicted SEED Role

"ATP-dependent helicase DinG/Rad3" in subsystem DNA repair, bacterial DinG and relatives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (705 amino acids)

>LRK53_RS03855 ATP-dependent DNA helicase DinG (Rhodanobacter sp000427505 FW510-R12)
MLTDTTKDAIRAAYARLKDGLPGFRARASQGRMIAETAKAFARAGGVAAVEAPTGTGKSM
AYLIAGVEVARFQKKRLLIATATVALQEQLVQRDIPLYLRLNGIEAKVALAKGRGRYLCP
RNLLMAANSIHDAQLGLAGFEADLLLWNKPPQPRDKQALAKLRGAFDRREWDGDMDSAPE
PVSELLRPMITTSAGGCTNRKCGQFMVCPFFVARRAVDDAEIIVANQDLVLADLTMPGEA
DGGAEPGWGGVILPRPDETLYVFDEAHHLPGKAIDRGAAEVHITASVRQLSRLGRQVHAA
YSLTDKESLGRLTLDAGDARLQELSDTLEELEKAIRLGWLPDPAETEPMYRGSLGQLPSP
WVQQARALSLLTGEVQRWLGAVRRAVVEMTDGGPTQEALSRELGIALERVGRQAACWRAW
SADDPDDAPPLARWVTLGADQQLVCHASAVSAAGLLREVLWGNASGVLLTSATLSAGGNF
RNFADAVGLPDDALTLSLPSPFDLAAQARLEVPSMRTLPDTREAHAEEISEWLAENLDWD
AGNLVLFTSRTKLDRVLQKLPIAQVRKVRAQGSLGKSQLVAEHCADIEAGKGSTLFGLAS
FGEGLDLPGKLCETVVITQLPFAVPTDPVGATYAEWLESRGRNPFIEVSIPEATRLLTQY
CGRLIRNESDHGRIVLLDRRVVTKRYGSGMLKALPPFRRVIERTA