Protein Info for LRK53_RS03425 in Rhodanobacter sp000427505 FW510-R12

Annotation: insulinase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 953 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00675: Peptidase_M16" amino acids 57 to 194 (138 residues), 56.4 bits, see alignment E=3.3e-19 amino acids 524 to 652 (129 residues), 45.7 bits, see alignment E=6.6e-16 PF05193: Peptidase_M16_C" amino acids 214 to 388 (175 residues), 95 bits, see alignment E=5.1e-31 amino acids 679 to 857 (179 residues), 91.8 bits, see alignment E=5e-30

Best Hits

KEGG orthology group: None (inferred from 63% identity to xcc:XCC3524)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (953 amino acids)

>LRK53_RS03425 insulinase family protein (Rhodanobacter sp000427505 FW510-R12)
MKKKPLVLLVAGLLTLVGGVPLALAAPTPDSAVAVALTQQIPELAWTRFILPNGLTVVVH
EDRKAPVVAVSVWYHVGSSYEPKGKTGFAHLFEHLMFQGSENHKDEFFKPFELAGATDQN
GTTWLDRTNYFETVPTSALDMALWMESDRMGHLLGAIGQPQLDEQRGVVQNEKRQGENQP
YGRASELIQAEAFPANHPYHHDTIGSMDDLNAASLGDVKQWFRDYYGAANTVVVLSGDIT
PALAKEKMLTYFGDIAAGPQVPRPQPWIAPRDKSTRGSMTDNVAQVRIYREWNVPGRGSR
DENLLELAAAVLGGSKTSRLYQRLVYRDKLADDVSVDVEQHVLASLFNLQVDVKKGADPA
KVEAAIADEWRKFLKDGPSADELARVKTETRASFVRGLEKVNTQASILAQGQLYRDDPGA
YLKDFREYMAATPAQVSAVANKWIARGDYTLTVVPGKVEATDMATVAGRAAASGALAPVL
SAKGDYRTVKSDLDRSKGVPEVGVFPDLSFPALQRGKLDNGVEVILAERHTVPAVQLQLL
FDAGYAADQDRKLGTSSFTMSMLDEGTKTLDSVEIAKRKQRLGAIIASGCGLDYCNATLN
ALDDQLKPSLELFADIVRNPAFREADIGRLRGQWLARIAQEKSQPTGIALRTLPPLLYGK
GHAYAIPFTGTGTEASITSITAADMRAFMGDFIRPDNLRILVAGDTTLDRIIPPLNAAFG
NWKAPVGKVPAKNIGKVAPPKQVRVYLVDRPGAQQSLILAGSLAPSTEAPDNLEIQTMNG
AFGGTFTSRLNMNLREDKHWAYGAFSFLQNAQGQRPFMLYAPVQTDKTAPSVAEMLKEAK
AVIGDQPLTAQEIGKIKVGDVRSMPGSYQTTAAVMGALQGIALYKRPDDYVQTLKSRIEA
QTDASVEAAAKQVIHPDQLTWVIVGDLNKIEAPIRALKLGEVQVLDADGKPVK