Protein Info for LRK53_RS02980 in Rhodanobacter sp000427505 FW510-R12

Annotation: aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 884 TIGR02414: aminopeptidase N" amino acids 17 to 881 (865 residues), 1082.8 bits, see alignment E=0 PF17900: Peptidase_M1_N" amino acids 110 to 197 (88 residues), 34.7 bits, see alignment E=4e-12 PF01433: Peptidase_M1" amino acids 236 to 445 (210 residues), 185.2 bits, see alignment E=2.8e-58 PF11940: DUF3458" amino acids 455 to 560 (106 residues), 89.9 bits, see alignment E=2.3e-29 PF17432: DUF3458_C" amino acids 564 to 882 (319 residues), 324 bits, see alignment E=2.5e-100

Best Hits

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.2

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (884 amino acids)

>LRK53_RS02980 aminopeptidase N (Rhodanobacter sp000427505 FW510-R12)
MHALPQAATPSLIRLRDYRAPAWRVEAIELDFDLGIDASEVLARLHLRRDVAQDAPLRLD
GENLQLLVIALDGRTLSAGEYRYDDSVLVVDGVRDGSVLETRVRLRPAANTALEGLYLSG
PRKTGFLLTQCEAEGFRHITFFPDRPDVLSRYTVTLRADRARFPVLLAGGNPDGAGELEG
GRHWARFVDPHPKPSYLFALVAGRLEVIERDYVTADGRAVQLKIWAEADAIGRCHYAMDA
LERAMRWDEQTYGRNYDLDVFHVVATHDFNMGAMENKGLNIFNAKCLLAEPDSTTDEEYR
HVEAVVAHEYFHNWSGNRVTCRDWFQLSLKEGLTVFREQSFSADMNSAPLKRIEDVALLR
RAQFPEDAGPLAHPVRPAQYSEINNFYTATVYEKGAELVRMLASALGRDGFRRGMDRYFE
RNDGHAATLEDFLAALGEANGSDLTPYLAWYAQAGTPRLKAHGHYDAAAHTYTLTLAQQI
PAGHGAEPRAPLPIPVKLALFTPHGDMLPLHLDGQTSKPVTELVVVLDRAERNFVFTDVG
AAPVPSLLRGFSAPVILEYDYTPDELALLLAHDVDGFNRWEASQQLAARAYEELRDGTAG
AALHAWCDALARLFDGAAVDDALLADLLTPPGEIELAERETAIDPQRIHQSRQALQRQLA
ERLGAENLQRRYLALLAQTGIELDASSQARRRLQRRVLELLALLDPTGAGALAATQYRDA
PGMTDRLAALSVLVRSGAAQAAAALRDYRERYAGNALALDKWFAVQAQLPGEPALNRVRQ
LERDDAFTLKNPNRVQSLLGAFVRSNPSGFHRADGAGYRLLGERLVALDALNPQVAARLA
TAFNGWQRLEPRRREAAQAAIVELARQPGLSRNLAEIIDSVLNH