Protein Info for LRK53_RS00865 in Rhodanobacter sp000427505 FW510-R12

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF12146: Hydrolase_4
  • amino acids 37 to 269 (233 residues), 217.4 bits, E=2.8e-68
• PF00561: Abhydrolase_1
  • amino acids 40 to 131 (92 residues), 42.5 bits, E=9.7e-15
• PF12697: Abhydrolase_6
  • amino acids 41 to 243 (203 residues), 56.3 bits, E=1.2e-18

Best Hits

KEGG orthology group: None (inferred from 47% identity to cai:Caci_7836)

Predicted SEED Role

"Lysophospholipase (EC 3.1.1.5); Monoglyceride lipase (EC 3.1.1.23); putative" (EC 3.1.1.23, EC 3.1.1.5)

MetaCyc Pathways

• monoacylglycerol metabolism (yeast) (2/4 steps found)
• phospholipid remodeling (phosphatidylethanolamine, yeast) (2/4 steps found)
• triacylglycerol degradation (1/3 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.5

Use Curated BLAST to search for 3.1.1.23 or 3.1.1.5

Protein Sequence (293 amino acids)

>LRK53_RS00865 alpha/beta hydrolase (Rhodanobacter sp000427505 FW510-R12)
MHAVLQNRPADGPEPTAWLAMADGQQLFLRDWPLAGARGAVLLVHGLGEHSGRYQRLATW
FNRRGYAVRGYDQRGHGRSPGRRGGLRHGDDLLEDLATVYYDYAGGLPHPPLLLGHSMGG
LVAVRAVLDGRVEPLALLLSSPALRTRESPRMIALARLLARVAPNLPLRNGLDFDQLSHD
RQVVADYRRDPLRHGWITPRLADFIFRAGAACIADAARLALPTLLLVADGDGIVDPSGSR
EFARQATSTGQLTTRFFSLLYHELFNENEPGRGQVLMQLGDWLGRQDAPAPHR