Protein Info for LRK53_RS00715 in Rhodanobacter sp000427505 FW510-R12

Annotation: insulinase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00675: Peptidase_M16" amino acids 65 to 169 (105 residues), 50.9 bits, see alignment E=1.6e-17 PF05193: Peptidase_M16_C" amino acids 210 to 387 (178 residues), 94.1 bits, see alignment E=1e-30

Best Hits

KEGG orthology group: None (inferred from 46% identity to gvi:glr3687)

Predicted SEED Role

"FIG00481622: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (491 amino acids)

>LRK53_RS00715 insulinase family protein (Rhodanobacter sp000427505 FW510-R12)
MSCRKNACRLAVFTAILVATGNVAAADFPATPPAPGPAPQLSVPTPTTQTLANGLQVVSV
RRGGLPLVTAQLIVRRGGEMDPPALAGLADLTANLLTKGAAGRSAPQIAAAAEALGGSLD
AAAGWDESAVGITVTTPKLPQALGLLAEVVRQPDFSAEELKRAQAQALDDLRLTLSRPTA
LASLAASRGVFGAGAYGHSRGGTPASIARIGRADVQRLHAALYRPDNAILVLAGDITPAQ
AQQLAQASFGDWRKPTTPLPARPAGRAASQLPRMLLIDQRGAGQAGVVAAHAAPPRGDGD
YYVGTLANAVLGGSYSARLNQEIRIKRGLSYGATSRLEPLRDAGLWLASAQTKNPSAAPV
VELMLGEFKRLGDSRIGVDELAARKATLIGGYGRSLETTTGLAGQVGELAVYGVPLDEIG
KYVARVQAVTPKQIEKYAKRHLAAGAGTVVVVGDAVLFAADIRKAHPQAALLQSTALDLD
SPTLQPAGSRK