Protein Info for LRK53_RS00705 in Rhodanobacter sp000427505 FW510-R12

Annotation: efflux RND transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1055 signal peptide" amino acids 12 to 16 (5 residues), see Phobius details amino acids 33 to 36 (4 residues), see Phobius details transmembrane" amino acids 17 to 32 (16 residues), see Phobius details amino acids 334 to 353 (20 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details amino acids 387 to 411 (25 residues), see Phobius details amino acids 431 to 451 (21 residues), see Phobius details amino acids 465 to 490 (26 residues), see Phobius details amino acids 536 to 556 (21 residues), see Phobius details amino acids 870 to 889 (20 residues), see Phobius details amino acids 896 to 915 (20 residues), see Phobius details amino acids 921 to 946 (26 residues), see Phobius details amino acids 971 to 993 (23 residues), see Phobius details amino acids 1000 to 1025 (26 residues), see Phobius details PF00873: ACR_tran" amino acids 7 to 1024 (1018 residues), 923.1 bits, see alignment E=2e-281 PF02355: SecD_SecF_C" amino acids 332 to 489 (158 residues), 20.9 bits, see alignment E=2.1e-08

Best Hits

Predicted SEED Role

"RND multidrug efflux transporter; Acriflavin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1055 amino acids)

>LRK53_RS00705 efflux RND transporter permease subunit (Rhodanobacter sp000427505 FW510-R12)
MNIFAPLIRRPVGTSLLALGLMLAGLWAYLLLGVAALPSLDFPGVYVVASQPGASAQTMA
NTVLAPLERHLGRIPGVDEMYGNASEGQASVMVRFTFDRTADSAARDVQAAINAAAVDLP
TGMPSLPQYFKFDTSQIPILFLTLTSTGLPQDQLFDLADTMLKPAVAQIDGVAQVQVFGG
TPHAVRIELDNGALAAKGLTTNDVANALRAANVTSPQGTLSDGHTQMTVSASDSLQTPAE
FARLLISVRNGTPVRLSDVAKVYSGQQDEYQAAWFNDARAVGLQISKRPEANAVATVEAI
RARLPQLRASLPSSVTMTPVFDLTQTTKSALHEVQVALLISIAMVVLVMLVFLRRLRPTL
IATLSVPLSLAGAFVVMWTLGYTLNTLSLVALVLCIGFVVDDAIVVIENIVRHMERGEPP
MEAALAGVREIGFTVVSITLSLVAVFAPLLFGNNILIMLLREFSVTLTAAVVISALVSLT
LTPALCAWLLSHEPEHTRQPGRIEQAVERFDRRLLHIYERALDWAMHHRRIMRWQPLTLL
ILTFVLGFAVAKTAGGTFMPDEDTGQLQVDISADANISPAELTARALAVAKIMQADPAVL
DQLTMLGRDGGGGGAVGNNAQMFVDLKPRGSGPGERREGIKQVVERLSKQYDKLANVKVS
VSAAQFLGGGGSGDKGGQYEFQLVSTNGGDLQPWALRMVRQLRAMKEFRDVSSNFDQVGK
QQLLKIDREAAARLHVGVGTIDSALYNAFGQRQVSQIYSDINQYAVVLSTGAAERVSPES
LLDVRVRNEQGRMIPLSALATIAPNLSPLRIRHHNQLEAATISYNLAKDVTQDVGVKLVE
QAAYAARLPAGMRVDFTGANQRLKQAQSNGMVLLLGSILAMYIVLGILYESLGHPLTILS
TLPAAGAGAFLAMLVTQTQISLMAIIAVLMLIGIVKKNAILMVDFALVAERERGLPAPEA
IREAALVRFRPITMTTLVAMGAALPLAIGFGIGSEMRQPLGIAIVGGLLVSQLLTLLSTP
AIYLWNHDRKIRKAARRERKAEKKRLKALGGTQAA