Protein Info for LRK53_RS00360 in Rhodanobacter sp000427505 FW510-R12

Annotation: NAD(P)H-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 190 PF03358: FMN_red" amino acids 5 to 146 (142 residues), 111.4 bits, see alignment E=1.5e-36

Best Hits

Swiss-Prot: 51% identical to HBQR_BURSP: 2-hydroxy-1,4-benzoquinone reductase from Burkholderia sp.

KEGG orthology group: None (inferred from 76% identity to ade:Adeh_3197)

MetaCyc: 63% identical to NAD(P)H-nicotine blue oxidoreductase (Paenarthrobacter nicotinovorans)
RXN-13069 [EC: 1.1.1.328]

Predicted SEED Role

"NADPH:quinone oxidoreductase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.328

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (190 amino acids)

>LRK53_RS00360 NAD(P)H-dependent oxidoreductase (Rhodanobacter sp000427505 FW510-R12)
MTTFKVGYIVGGLAKGSINRLLSKALVRLAPPALQLVEIPIRDLPLYSYDYDADYPPVAR
AFKQAIAEVDAILFVTPEYNRSIPGGLKNAIDWASRPWGKNSFARKPSGVIGTSPGSIGT
AVAQQQLRGVLCFCNSPLMNTMEAYIQFKPGLISEDGTVSDESTTEFLSNYMKELHIFIE
RVLTVLPRED