Protein Info for LRK53_RS00255 in Rhodanobacter sp000427505 FW510-R12

Annotation: PQQ-dependent sugar dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 387 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF23500: DUF7133" amino acids 27 to 350 (324 residues), 60 bits, see alignment E=4.2e-20 PF22807: TrAA12" amino acids 28 to 359 (332 residues), 61.1 bits, see alignment E=1.2e-20 PF07995: GSDH" amino acids 130 to 355 (226 residues), 54.4 bits, see alignment E=1.9e-18

Best Hits

KEGG orthology group: None (inferred from 64% identity to gdj:Gdia_1425)

Predicted SEED Role

"Glucose/sorbosone dehydrogenases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (387 amino acids)

>LRK53_RS00255 PQQ-dependent sugar dehydrogenase (Rhodanobacter sp000427505 FW510-R12)
MRLLLPLLLGLSSLPALAAPPPLDRLTLPRGFHIALYSDQVPDARELALGAKGTVFVGSN
DAGKVYALTDNNGDGVADQVRVVASGLQLPVGVAFKGGDLYVSAVSCIVVLRDIENHLDD
PPKPAVVTDQLPSETHHGWKFIAFGPDGKLYVPIGAPCNICDPAPAHGKLIRMNADGSDW
QDVARGIRNSVGFDWQPGTKRLWFTDNGRDLMGDDMPSDELNEITGPDQHFGYPYCHQGD
TLDPEFGKGRRCKDYVPPVLKLGAHVGALGMRFYEGQQFPASYRGAIIVAEHGSWNRTKK
SGYRVMTVRLNGSKVVAYEPLITGFEQNESAWGRPVDVQPLPDGSVLVSDDLAGAVYRVT
YGSRDSGDGIRDSQERPRASVDAPASP