Protein Info for KEDOAH_25125 in Escherichia coli ECRC99

Annotation: acetyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13673: Acetyltransf_10
  • amino acids 27 to 131 (105 residues), 54.8 bits, E=1.4e-18
• PF13508: Acetyltransf_7
  • amino acids 51 to 122 (72 residues), 42.5 bits, E=1e-14
• PF00583: Acetyltransf_1
  • amino acids 53 to 121 (69 residues), 43.3 bits, E=6.1e-15

Best Hits

Swiss-Prot: 55% identical to YJAB_ECOLI: Peptidyl-lysine N-acetyltransferase YjaB (yjaB) from Escherichia coli (strain K12)

KEGG orthology group: K03827, putative acetyltransferase [EC: 2.3.1.-] (inferred from 99% identity to eok:G2583_0719)

MetaCyc: 55% identical to peptidyl-lysine N-acetyltransferase YjaB (Escherichia coli K-12 substr. MG1655)
2.3.1.-

Predicted SEED Role

"Putative acetyltransferase"

KEGG Metabolic Maps

• 1- and 2-Methylnaphthalene degradation
• Alkaloid biosynthesis I
• Alkaloid biosynthesis II
• Anthocyanin biosynthesis
• Benzoate degradation via CoA ligation
• Biosynthesis of terpenoids and steroids
• Biosynthesis of type II polyketide backbone
• Biosynthesis of unsaturated fatty acids
• Butanoate metabolism
• Carotenoid biosynthesis - General
• Diterpenoid biosynthesis
• Ether lipid metabolism
• Ethylbenzene degradation
• Fatty acid biosynthesis
• Glycerophospholipid metabolism
• Glycosphingolipid biosynthesis - ganglio series
• Histidine metabolism
• Limonene and pinene degradation
• Lipopolysaccharide biosynthesis
• Lysine degradation
• Phenylalanine metabolism
• Tyrosine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.-

Use Curated BLAST to search for 2.3.1.-

Protein Sequence (145 amino acids)

>KEDOAH_25125 acetyltransferase (Escherichia coli ECRC99)
MLKIRMSRPSEAPEIIQIWKNSVDATHDFLTAHDRQEIEKEVVSFFSETPVLVATNQEDQ
PLGFMFLHEGHLEALFVDASARGLGVGKHLISHALAQHPDLSVDVNEQNHQAVGFYQHMG
FKLSGRSERDNQGRPYPLLHLYNAM