Protein Info for KEDOAH_23595 in Escherichia coli ECRC99
Name: citE
Annotation: citrate lyase subunit beta
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to eoi:ECO111_1250)Predicted SEED Role
"Citrate lyase beta chain (EC 4.1.3.6)" (EC 4.1.3.6)
MetaCyc Pathways
- citrate degradation (2/2 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 4.1.3.6
Use Curated BLAST to search for 4.1.3.6
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (318 amino acids)
>KEDOAH_23595 citrate lyase subunit beta (Escherichia coli ECRC99) MKNRLSPWNLGATLYMPATREDIADAVLHGKIPSLRSLVICLEDAVSEADIPVALKNLEH LLHELSNSMSSLGKNDWPLVFIRPRHAEMGRWLKAHYDLSAVDGFVLPKFTLSSLAEWWD IMVGTHLCMMPTLETEDVFDVVQMRELATRLEEHPCHDRIIALRIGGNDLMNVVSLRRPR DLTLYDSPMGYVIKMLVSVFGPRDFALTAPVCEHIDDHAVMARELALDMAHGLVGKTAIH PGQIEVIQNALMVTQGEHSDALRILNSTQAVFKSQGAMCEPATHRRWAAGILDRARFYGL QNEQSADGIRLLTVTQHH