Protein Info for KEDOAH_19385 in Escherichia coli ECRC99

Annotation: Protein involved in detoxification of methylglyoxal

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 759 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF10971: DUF2773" amino acids 679 to 759 (81 residues), 134.4 bits, see alignment E=6.1e-44

Best Hits

KEGG orthology group: None (inferred from 100% identity to eok:G2583_0500)

Predicted SEED Role

"Protein YkiA" in subsystem CBSS-562.2.peg.5158 SK3 including

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (759 amino acids)

>KEDOAH_19385 Protein involved in detoxification of methylglyoxal (Escherichia coli ECRC99)
MNRINILVICMVLFFMTGNACATEWISSEDLITSDFHLMTADERNVVKAATDDSMEAAYM
LKDNIRWYYHNGDLSLPANFSNKNKLVVNGNLTISGDYDDYLSGNGHLIVLGNVIVDNFI
NHDFAYVKGQMTAKGLVYADYNDHNFEVMKGISARGIIVSDKATQFEVIKAEFYINEDGS
GEGYNWDENIQKAYSLVTADLYDHTEIETDNISNAYPDYDSVADNIVQGLPLFRDKAAPE
INEKLKWIETGKLDNFPANKIKHQDPLVARFLTHTESLSPAVMLQLLQHPDDQTRESMAQ
SWPAQQMHWLTDELIKDEAVARGLVKNSNISADVNKKLMSVPVESVQLEQARQDNLSPDI
VASLSHSPFLSVRKTLLSHYDYAWLVPTAVADELINNEDPELRERITGADLTAQQAVMLS
KDKSLKVREALARTLTELKITQLSATLRTEDIERIAEQMYLDNKENKNIVKVLLIALPEM
RQLSLAKEDVHNLREGARYLTSKDVISYLLTQHDVPTVWDELARDKLLPLEYKKQLWQRT
LNLMMSKRQEDQEQAYEVQLALIDNGVVDEEMLNNAIDLLVDLPAEYRYRMRNQLFDNKE
LPSGIINKLDQQYRFNSDWALAVVSMKNSTRRQSERGLHRWNHEDSDIFAELATIKDKSD
DEWWRALLQSRNDHLRQTALRNAHTPASLLTTLTESQDRSLAINNPQLAADVKTVWLKED
PSLLLFVDKPDLSQLRDLVKTGATRKIRNEARHRLEEKQ