Protein Info for KEDOAH_18845 in Escherichia coli ECRC99

Name: rclC
Annotation: reactive chlorine species resistance protein RclC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 197 transmembrane" amino acids 14 to 35 (22 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 113 to 133 (21 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details PF04224: DUF417" amino acids 2 to 182 (181 residues), 267.3 bits, see alignment E=2.6e-84

Best Hits

Swiss-Prot: 98% identical to RCLC_ECOLI: Inner membrane protein RclC (rclC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ece:Z0378)

Predicted SEED Role

"Putative inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (197 amino acids)

>KEDOAH_18845 reactive chlorine species resistance protein RclC (Escherichia coli ECRC99)
MEKYLHLLSRGDKIGLALIRLSIAIVFMWIGLLKFVPYEADSITPFVANSPLMSFFYEHP
EDYKQYLTHEGEYKPEARAWQSANNTYGFSNGLGVVEVIIALLVLANPVNRWLGLLGGLM
AFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLVLKDTLMLAGAVMIMADSARE
ILKQGSNESSSTLKTEY