Protein Info for KEDOAH_18560 in Escherichia coli ECRC99

Annotation: DNA repair protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 883 PF13476: AAA_23" amino acids 268 to 497 (230 residues), 57.9 bits, see alignment E=3.3e-19

Best Hits

KEGG orthology group: None (inferred from 64% identity to vcj:VCD_003715)

Predicted SEED Role

"ATPase involved in DNA repair"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (883 amino acids)

>KEDOAH_18560 DNA repair protein (Escherichia coli ECRC99)
MSVSWTKADFFKCALQVNPAGYSKYRGKESLSEDTYNQKLLESCLEAGIQIVGVADHGAV
NAVDRIRQLFKEHGIVVFPGFEICSSEKIHFVCLFDENRTVQELERCLSNLGYENPDDCI
SPSRLSAIQIIEKVECLGGFIFAAHSTNDNGVLKCRMNHIWKERGLLAAQIPGTVDDLKG
VEDDFYRKAILNKLPDYRRERPIAIINAADVAQPEEIKTPGASCLIKMTRPCFSSFKQAF
LDPESRVRLNADKPHCYASAIENIHFTGGYLDETNITFSDHLNAVIGGRGTGKSTLLEAI
RFALGKQPFGDSAQKQHSAIIKTNLGNGTLVQLQVRSAMMQGRTFTISRKFGGKSIVTDS
EGKVSSYTPDDLLPRLELYGQNEIYEMTRDIHSRNRLVERFLEGDHSKYDVIIDKVLSRL
EESSITILNALEQKAEIELEVARLPKLLEQAEQFKQLGLDEKLKIVPLLEKEKQLSLRHQ
EELSRVKDVLQKLKDSLPDLAYLDDGVINVMPHHSLFLQQRDVLQRAQEQLSTLVQHIDE
TLQRSFAELAPLQLELSDLIGAEEAQLEKAFKDIPASQGKSGRQIGAEYQILLRQIASIR
PKATELENWQKQLDELYQQRKRHLLELIQARAQRSAALAKSVKRLNRRLDEKVRLNLQPE
GNRQPLLHFLEQCNLEGVGSRRLAWVLEHDFSPENLVESIRLGEQALHNAGWGITPTVIQ
ALLRLSEKQLLELEALSLPDTMQIELNVMHDGGGVLWRPIDELSTGQQCTAVLHLLLLDN
KDPLILDQPEDNLDNAFIAERIVTELRRAKLSRQFLFATHNANIPVFGDAEWIGVLSVEE
GKGRILPEQQGAIDLPEIQCLAANILEGGQSAFNQRREKYGFK