Protein Info for KEDOAH_18255 in Escherichia coli ECRC99

Name: tssL
Annotation: Type VI secretion system protein TssL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 transmembrane" amino acids 214 to 235 (22 residues), see Phobius details TIGR03349: type IV/VI secretion system protein, DotU family" amino acids 32 to 242 (211 residues), 214.2 bits, see alignment E=9e-68 PF09850: DotU" amino acids 33 to 233 (201 residues), 195.9 bits, see alignment E=3e-62

Best Hits

KEGG orthology group: K11892, type VI secretion system protein ImpK (inferred from 100% identity to eok:G2583_0231)

Predicted SEED Role

"Outer membrane protein ImpK/VasF, OmpA/MotB domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (253 amino acids)

>KEDOAH_18255 Type VI secretion system protein TssL (Escherichia coli ECRC99)
MDEGSLSLPPFTGYDEKSLRDYHLALHGNSLNPMIDAATPLLGMVMRLSTMNSQTMPEHL
FAQVVTDVQAVEQLLQEQGYEPGVIISFRYILCTFIDEAALGNGWSNKNEWIKQSLLVHF
HNEAWGGEKVFILLERLIREPKRYQDLLEFLWLCFSLGFRGRYKVAVQDQGEFEQIYRRL
YHVLHKLRGDAPFPLLHQDKKTQGGRYQLISRLTVKHIFCGGVVVLALFYLFYLLRLDSQ
TQDILHQLNKLLR