Protein Info for KEDOAH_16995 in Escherichia coli ECRC99

Name: yjjX
Annotation: inosine/xanthosine triphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 170 TIGR00258: inosine/xanthosine triphosphatase" amino acids 6 to 170 (165 residues), 239.1 bits, see alignment E=1.4e-75 PF01931: NTPase_I-T" amino acids 7 to 165 (159 residues), 174.1 bits, see alignment E=1e-55

Best Hits

Swiss-Prot: 100% identical to NCPP_ECO57: Inosine/xanthosine triphosphatase (yjjX) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 98% identity to eco:b4394)

MetaCyc: 98% identical to inosine/xanthosine triphosphatase (Escherichia coli K-12 substr. MG1655)
RXN0-5073 [EC: 3.6.1.73]; 3.6.1.73 [EC: 3.6.1.73]

Predicted SEED Role

"Inosine/xanthosine triphosphatase (EC 3.6.1.-)" (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-

Use Curated BLAST to search for 3.6.1.- or 3.6.1.73

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (170 amino acids)

>KEDOAH_16995 inosine/xanthosine triphosphatase (Escherichia coli ECRC99)
MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASIAVESGVPEQPFGSEETRAGARNRVA
NARRLLPEADFWVAIEAGIDGDSTFSWVVIENTTQRGEARSATLPLPAVILEKVREGEAL
GPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVILALSPFHNAVY