Protein Info for KEDOAH_15540 in Escherichia coli ECRC99

Name: phnC
Annotation: phosphonate ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 273 PF00005: ABC_tran" amino acids 20 to 170 (151 residues), 111.8 bits, see alignment E=2.1e-36 amino acids 168 to 192 (25 residues), 25.2 bits, see alignment (E = 1.1e-09)

Best Hits

Swiss-Prot: 93% identical to PHNC_ECO57: Phosphonates import ATP-binding protein PhnC (phnC) from Escherichia coli O157:H7

KEGG orthology group: K02041, phosphonate transport system ATP-binding protein (inferred from 93% identity to ecs:ECs5088)

Predicted SEED Role

"Phosphonate ABC transporter ATP-binding protein (TC 3.A.1.9.1)" in subsystem ABC transporter alkylphosphonate (TC 3.A.1.9.1) (TC 3.A.1.9.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (273 amino acids)

>KEDOAH_15540 phosphonate ABC transporter ATP-binding protein (Escherichia coli ECRC99)
MQTIICVEQLSKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSA
GSHIELLGRTVQREGRLARDIRKSRANTGYIFQQFNLVNRLSVLENVLIGALGSTPFWRT
CFSWFTREQKQRALQALTRVGMAHFAYQRVSTLSGGQQQRVAIARALMQQRVAIARALMQ
QAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQG
HVFYDGSSQQFDNERFDHLYRSINRVEENAKAA