Protein Info for KEDOAH_04180 in Escherichia coli ECRC99

Annotation: DUF4132 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 579 PF13569: DUF4132" amino acids 303 to 488 (186 residues), 181.7 bits, see alignment E=6.5e-58

Best Hits

KEGG orthology group: None (inferred from 100% identity to ece:Z3286)

Predicted SEED Role

"Molybdate metabolism regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (579 amino acids)

>KEDOAH_04180 DUF4132 domain-containing protein (Escherichia coli ECRC99)
VALAEALVKKDDKRKHTLLVSLLNANPLFVEKLVIGLSSQAANLLQQCQQLLNSRNEDFA
NSEILPMVLVSPPWETQNKNNDNSPVGKYPAKIPPLPLFYQPPLWTRPKLKNSSKVLPDS
ALQHLGEMLRFPQEEALYPGLLQVKDACTADSLAEFAWDLFTAWLTAGAPSKESWAFTAL
GVLGNDDTARKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNGIAQKLKFKALQ
ERAKEKIAGIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGSRQFTVSFDETLKPFVRD
VSGSRLKDLPKPNKSDDESQANDAVNRYKLLKKDARTVAAQQVARLESAMCLRRRWSPEN
FQLFLVEHPLVRHLTRRLIWGVYSTENQLLTCFRVAEDNSYSTADDDLFTLPEGDISVGI
PHVLEISPTDATAFGQLFADYELLPPFRQLDRNSYALTEAERNASELTRWAGRKCPSGRV
MGLANKGWIKGTPQDGGWIGWMIKPLGRWSLIMEIDEGFAVGMSPAELSAEQILSKLWLW
EGNAESYGWGSNSTQEAQFSVLDAITASELINDIEALFE