Protein Info for KEDOAH_00630 in Escherichia coli ECRC99

Name: slyA
Annotation: transcriptional regulator SlyA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 144 PF12802: MarR_2" amino acids 29 to 87 (59 residues), 49.7 bits, see alignment E=5e-17 PF01047: MarR" amino acids 29 to 87 (59 residues), 60.1 bits, see alignment E=2.3e-20 PF13463: HTH_27" amino acids 29 to 96 (68 residues), 33.2 bits, see alignment E=8e-12

Best Hits

Swiss-Prot: 99% identical to SLYA_ECO8A: Transcriptional regulator SlyA (slyA) from Escherichia coli O8 (strain IAI1)

KEGG orthology group: K06075, MarR family transcriptional regulator, transcriptional regulator for hemolysin (inferred from 99% identity to eco:b1642)

Predicted SEED Role

"Transcriptional regulator SlyA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (144 amino acids)

>KEDOAH_00630 transcriptional regulator SlyA (Escherichia coli ECRC99)
LESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQ
PSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISA
EELEQLITLIAKLEHNIIELQAKG