Protein Info for KDGMDA_24645 in Klebsiella pneumoniae MKP103

Annotation: invasion regulator SirB1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 transmembrane" amino acids 99 to 121 (23 residues), see Phobius details PF13369: Transglut_core2" amino acids 34 to 185 (152 residues), 154.5 bits, see alignment E=1.6e-49 PF13371: TPR_9" amino acids 188 to 260 (73 residues), 79.8 bits, see alignment E=1.3e-26

Best Hits

Swiss-Prot: 82% identical to SIRB1_SALTI: Protein SirB1 (sirB1) from Salmonella typhi

KEGG orthology group: None (inferred from 99% identity to kva:Kvar_1951)

Predicted SEED Role

"FIG002708: Protein SirB1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (270 amino acids)

>KDGMDA_24645 invasion regulator SirB1 (Klebsiella pneumoniae MKP103)
MGSLADFEFNKAPLCDGMVLISEQVRDDFPSRFVEEELQRLLRLAQEEIAPSWDQERQIE
RLLELFYDEWGFGASQGVYRLSDALWLDKVLVNRQGSAVSLGAILLWIAQRLALPVVPVI
FPTQMLLRADPETSEEMWLINPFNGETLDEHTLEVWLKGNIGPVAELFNEDLDEADNAEV
IRKLLDTLKSALMEERQMELALRASEALLQFNPEDPYEIRDRGLIYAQLDCDHVALLDLS
YFVEQCPEDPISEMIRAQINTISHKQITLH