Protein Info for KDGMDA_24610 in Klebsiella pneumoniae MKP103

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 PF08376: NIT" amino acids 41 to 277 (237 residues), 168.2 bits, see alignment E=4.3e-53 PF03861: ANTAR" amino acids 329 to 381 (53 residues), 66 bits, see alignment 2e-22

Best Hits

Swiss-Prot: 75% identical to NASR_KLEOX: Nitrate regulatory protein (nasR) from Klebsiella oxytoca

KEGG orthology group: None (inferred from 100% identity to kpu:KP1_3337)

Predicted SEED Role

"Response regulator NasT" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (393 amino acids)

>KDGMDA_24610 transcriptional regulator (Klebsiella pneumoniae MKP103)
MNNTTGHAHDATAWLQLARRLQKQQLQQFSQLGELASQLSALVHMLQCERGASNIYLCSG
GLLYTAECRAGGALVDERLALFYASLERARAVAGSALCWRIARAVDELAQLPALRAQIGR
RQIAAEAATEQFSRVIRHLLNIAPQLNDSIDDPPVAGRMVALYSFMQGKELVGQERALGA
LGFTRGEFSDSLRQQLVDRIDGQQPCFDSFQALGSPATVQLFRTQCHAGLDIEQLRRIAC
TRQPAADGGETALRWFGLQTQRLEQLREVEEQLIDDLLDATDALLADDAPGWQAGEEDDC
VTPRLDKQLLPLVRQQAYELQQLSSQLASLKDALEERKLIEKAKSLLMTHQGMQEEQAWQ
TLRKMAMDKNQRMVEIARALLMVKAIWPLTPKE