Protein Info for JDDGAC_28440 in Escherichia coli ECRC98

Name: wcaD
Annotation: putative colanic acid polymerase WcaD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 7 to 24 (18 residues), see Phobius details amino acids 30 to 47 (18 residues), see Phobius details amino acids 55 to 72 (18 residues), see Phobius details amino acids 84 to 102 (19 residues), see Phobius details amino acids 116 to 138 (23 residues), see Phobius details amino acids 152 to 152 (1 residues), see Phobius details amino acids 172 to 191 (20 residues), see Phobius details amino acids 203 to 227 (25 residues), see Phobius details amino acids 243 to 265 (23 residues), see Phobius details amino acids 278 to 296 (19 residues), see Phobius details amino acids 327 to 347 (21 residues), see Phobius details amino acids 368 to 397 (30 residues), see Phobius details TIGR04010: putative colanic acid polymerase WcaD" amino acids 1 to 404 (404 residues), 868.5 bits, see alignment E=3.7e-266

Best Hits

Swiss-Prot: 100% identical to WCAD_ECOLI: Putative colanic acid polymerase (wcaD) from Escherichia coli (strain K12)

KEGG orthology group: K13620, putative colanic acid polymerase (inferred from 100% identity to ecf:ECH74115_2991)

MetaCyc: 100% identical to colanic acid polymerase (Escherichia coli K-12 substr. MG1655)
2.4.99.-

Predicted SEED Role

"Colanic acid polymerase WcaD" in subsystem Colanic acid biosynthesis

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>JDDGAC_28440 putative colanic acid polymerase WcaD (Escherichia coli ECRC98)
MSTSIRICSYLLLPLIYLLVNVKITQLGESFPITIVTFLPVLLLLFLERISVKKLMIALG
ICAGLTAFNYLFGQSLDASKYVTSTMLFVYIVIIIGMVWSIRFKTISPHNHRKILRFFYL
VVGLVVALAAVEMAQIILTGGSSIMESISKYLIYSNSYVLNFIKFGGKRTTALYFEPAFF
ALALISIWLSIKQFGIKTPKTDAMILAGIILSGSFSGVMTFILFYLLEWAFQYLNKEAIK
KKLPLALISLAVFLVGVVIAFPYISTRLGDLGTEGSSSYYRIVGPLVMVGYSLTHIDGVV
RFGSLYEYVASFGIFNGADVGKTIDNGLYLLIIYFSWFAVFLSLWYMGKVIKMMINAFGD
NRNFRVQLYLFTPVSLFFTGSIFSPEYAFLIVCPFILRKALNITR