Protein Info for JDDGAC_26750 in Escherichia coli ECRC98

Name: yfcC
Annotation: putative basic amino acid antiporter YfcC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 492 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 92 to 113 (22 residues), see Phobius details amino acids 134 to 152 (19 residues), see Phobius details amino acids 158 to 184 (27 residues), see Phobius details amino acids 194 to 213 (20 residues), see Phobius details amino acids 219 to 238 (20 residues), see Phobius details amino acids 273 to 296 (24 residues), see Phobius details amino acids 302 to 320 (19 residues), see Phobius details amino acids 339 to 357 (19 residues), see Phobius details amino acids 378 to 403 (26 residues), see Phobius details amino acids 410 to 410 (1 residues), see Phobius details amino acids 413 to 426 (14 residues), see Phobius details amino acids 439 to 457 (19 residues), see Phobius details amino acids 468 to 489 (22 residues), see Phobius details PF03606: DcuC" amino acids 1 to 487 (487 residues), 537 bits, see alignment E=1.7e-165

Best Hits

Swiss-Prot: 100% identical to YFCC_ECOLI: Putative basic amino acid antiporter YfcC (yfcC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b2298)

Predicted SEED Role

"Putative S-transferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (492 amino acids)

>JDDGAC_26750 putative basic amino acid antiporter YfcC (Escherichia coli ECRC98)
MPDTLVIIFFVAILTSLATWVVPVGMFDSQEVQYQVDGQTKTRKVVDPHSFRLLTNEAGE
PEYHRVQLFTTGDERPGLMNFPFEGLTSGSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDN
GILALIRHTRGNEILFIPALFILFSLGGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVL
VTYIATQIGFASSWMNPFCVVVAQGIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRV
KKNPLLSRVHESDRFFREKQADVEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEI
ASQFFTMGLVIGIIGVVFRLNGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGE
AGDASVLNTILNSIANAISGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGD
LVGVNRQVTVLAFQFGDGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSS
VVVIGAQLMGYH