Protein Info for JDDGAC_26420 in Escherichia coli ECRC98

Name: purR
Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 PF00356: LacI" amino acids 1 to 34 (34 residues), 42.8 bits, see alignment 5.5e-15 PF00532: Peripla_BP_1" amino acids 47 to 315 (269 residues), 310.2 bits, see alignment E=2.2e-96 PF13377: Peripla_BP_3" amino acids 156 to 299 (144 residues), 68.9 bits, see alignment E=8.9e-23

Best Hits

Swiss-Prot: 99% identical to CSCR_ECOLX: Sucrose operon repressor (cscR) from Escherichia coli

KEGG orthology group: None (inferred from 99% identity to ecy:ECSE_2661)

Predicted SEED Role

"Sucrose specific transcriptional regulator CscR, LacI family" in subsystem Sucrose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (317 amino acids)

>JDDGAC_26420 transcriptional regulator (Escherichia coli ECRC98)
MMTVSRVMHNAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGRKPSTLAVLAQDTATT
PFSVDILLAIEQTASEFGWNSFLINIFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLP
ESLYGENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYRQPLCFWLPESALATGY
RRQGFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNDHFKSGKPDFDVLICGNDRAA
FVAYQVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEGRE
GGSVTRIPCPLLIRCST