Protein Info for JDDGAC_24775 in Escherichia coli ECRC98

Name: espM2
Annotation: T3SS effector guanine nucleotide exchange factor EspM2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 196 PF03278: IpaB_EvcA" amino acids 40 to 177 (138 residues), 106.6 bits, see alignment E=5.4e-35

Best Hits

KEGG orthology group: K13743, protein IpgB2 (inferred from 100% identity to ece:Z3918)

Predicted SEED Role

"Uncharacterized fimbrial chaperone YehC precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (196 amino acids)

>JDDGAC_24775 T3SS effector guanine nucleotide exchange factor EspM2 (Escherichia coli ECRC98)
MPMNTTGMSFSSFGISCHRENSFRNSFRGKNDEVVKCSIGERTISFSVRKFSGNILETVR
RQSTKDIDEWIKDERIVYPSRVINQEIDNYCFQKNAKISTEERQRVFFLVSQENQLTLDV
KAAQSSINHVIMGSASFGKKMDALCDGMSRDVKNRTSDTIANLLADKFYQKHIDSDIDIV
KLRNDIPDYLMRAIQG