Protein Info for JDDGAC_22135 in Escherichia coli ECRC98

Name: mzrA
Annotation: EnvZ/OmpR regulon moderator MzrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 220 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 44 to 64 (21 residues), see Phobius details amino acids 68 to 89 (22 residues), see Phobius details amino acids 123 to 145 (23 residues), see Phobius details amino acids 155 to 176 (22 residues), see Phobius details amino acids 188 to 212 (25 residues), see Phobius details PF09335: SNARE_assoc" amino acids 48 to 174 (127 residues), 83.4 bits, see alignment E=9.4e-28

Best Hits

Swiss-Prot: 100% identical to YQJA_ECO57: Inner membrane protein YqjA (yqjA) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 100% identity to eco:b3095)

Predicted SEED Role

"DedA family inner membrane protein YqjA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (220 amino acids)

>JDDGAC_22135 EnvZ/OmpR regulon moderator MzrA (Escherichia coli ECRC98)
MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLPAAFLPGDSLLVLVGVL
IAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNWLSHLPAHYHQRAHHLFHK
HGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMSGLLWVLILTTLGYMLGKTPV
FLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGNRG