Protein Info for JDDGAC_18595 in Escherichia coli ECRC98

Annotation: toxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 662 PF07906: Toxin_15" amino acids 151 to 386 (236 residues), 154 bits, see alignment E=3.3e-49

Best Hits

KEGG orthology group: K06867, (no description) (inferred from 100% identity to ecf:ECH74115_5138)

Predicted SEED Role

"Ankyrin-repeat protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (662 amino acids)

>JDDGAC_18595 toxin (Escherichia coli ECRC98)
MVDNVTVSRVCIQSPSFVPDLDGEKNKSQLFVDDIVAYLKSPSVYSLEKEGPLNHFVNHC
SEVELGFYSDGAYSILVSRSKQQPEGMILTVSDADAINIVHISVSPVLIKFLDDIFTCLH
TYPDDESFTKEQIKANSKYDIVDYNCLLHFTGKPKSLIECRHFALQYCIDSMNEHTGKVP
LKAYYSSPEDIQKHIPFELEQQFNNLQKNPPPGTCVVASDKFGEALSVFFHRMEKEKLTH
MTAIVQSQTHAMAVRLRIKKTPAGETEYVVSFYDPNATNTAVRYKANNCDSFGSLQSFIN
IQQAKQKWVITDICSECVGITPYLPREQAHLLSGIENELQPPLSPPALFLLMRMGIYKNI
VLFFDKLKNSQEMTASKALDILAAKSPEGIYGLCVLLYHNTIDKFNDYITNLKELTRKYN
FSQEDLETLLLAKDNLGVSWIPRALKNNQNKIVKAWLLAIDDFEKEFGVNKNEILLRIGK
EIDSIDDLNSAIRTNDYNVVNILLANIKAKMFKNELNKEDILKLMAAREKVAGASDKWTK
ASGLYSAIVKGHTKIVAAWMETAEVIASHYENDKDVVRELLSLSRNNAVCSLYVASYKTM
SKQVIDVYLNAAIRLALQHGFTFDEILEQFTRDFDGKSFSLAVEKADDIYGSLAENIQNC
GW