Protein Info for JDDGAC_17960 in Escherichia coli ECRC98

Name: bioP
Annotation: biotin transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 29 to 47 (19 residues), see Phobius details amino acids 58 to 76 (19 residues), see Phobius details amino acids 79 to 82 (4 residues), see Phobius details amino acids 85 to 105 (21 residues), see Phobius details amino acids 112 to 130 (19 residues), see Phobius details amino acids 136 to 158 (23 residues), see Phobius details amino acids 172 to 191 (20 residues), see Phobius details amino acids 203 to 222 (20 residues), see Phobius details amino acids 234 to 253 (20 residues), see Phobius details amino acids 259 to 276 (18 residues), see Phobius details PF00892: EamA" amino acids 2 to 128 (127 residues), 35 bits, see alignment E=7.6e-13 amino acids 139 to 275 (137 residues), 45.4 bits, see alignment E=4.7e-16 TIGR00950: carboxylate/amino acid/amine transporter" amino acids 11 to 273 (263 residues), 309.7 bits, see alignment E=8.2e-97

Best Hits

Swiss-Prot: 100% identical to BIOP_ECOLI: Biotin transporter (bioP) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b3827)

MetaCyc: 100% identical to biotin transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-240

Predicted SEED Role

"FIG00639538: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (299 amino acids)

>JDDGAC_17960 biotin transporter (Escherichia coli ECRC98)
VALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFLPFLRTRGNSLKTVGLY
MLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIYDIMSKRRLRWGYAFSALL
AVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKRLMETRPMPQHNAFAWFYLGA
FLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIGYFMWNYGATQVDAGTLGIMNNM
HVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVHRKWVAPRSSQTADDRRRDCALSE