Protein Info for JDDGAC_16030 in Escherichia coli ECRC98

Name: epmB
Annotation: EF-P beta-lysylation protein EpmB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 TIGR00238: KamA family protein" amino acids 3 to 328 (326 residues), 519.2 bits, see alignment E=3.9e-160 TIGR03821: EF-P beta-lysylation protein EpmB" amino acids 15 to 335 (321 residues), 534.2 bits, see alignment E=9.3e-165 PF13353: Fer4_12" amino acids 112 to 180 (69 residues), 24 bits, see alignment E=4.5e-09 PF04055: Radical_SAM" amino acids 118 to 264 (147 residues), 43.7 bits, see alignment E=3.6e-15

Best Hits

Swiss-Prot: 97% identical to EPMB_ECOLI: L-lysine 2,3-aminomutase (epmB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to ecl:EcolC_3866)

MetaCyc: 97% identical to lysine 2,3-aminomutase (Escherichia coli K-12 substr. MG1655)
5.4.3.-

Predicted SEED Role

"Lysyl-lysine 2,3-aminomutase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>JDDGAC_16030 EF-P beta-lysylation protein EpmB (Escherichia coli ECRC98)
MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAGRNAKKLFALRVPRSFI
DRMEKGNPDDPLLRQVLTSQDEFVVAPGFSTDPLEEQHSVVPGLLHKYHNRALLLVKGGC
AVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEMIFSGGDPLMAKDHELDWLLT
QLEAIPHIKRLRIHSRLPIVIPARITDALVERFSHSTLQILLVNHINHANEIDETFRQAM
AKLRRAGVTLLNQSVLLRGVNDNAQTLANLSNALFDAGVMPYYLHVLDKVQGAAHFMVSD
DEARQIMRELLTLVSGYLVPKLAREIGGEPSKTPLDLQLRQQ