Protein Info for JDDGAC_15970 in Escherichia coli ECRC98

Name: yjeM
Annotation: glutamate/gamma-aminobutyrate family transporter YjeM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 68 to 86 (19 residues), see Phobius details amino acids 117 to 134 (18 residues), see Phobius details amino acids 146 to 169 (24 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details amino acids 228 to 249 (22 residues), see Phobius details amino acids 296 to 318 (23 residues), see Phobius details amino acids 348 to 368 (21 residues), see Phobius details amino acids 380 to 400 (21 residues), see Phobius details amino acids 420 to 439 (20 residues), see Phobius details amino acids 451 to 469 (19 residues), see Phobius details PF13520: AA_permease_2" amino acids 1 to 456 (456 residues), 86.9 bits, see alignment E=1.5e-28 PF00324: AA_permease" amino acids 9 to 450 (442 residues), 43.8 bits, see alignment E=1.5e-15

Best Hits

Swiss-Prot: 98% identical to YJEM_ECOLI: Inner membrane transporter YjeM (yjeM) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to ecc:c5244)

Predicted SEED Role

"Putative amino acid permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (485 amino acids)

>JDDGAC_15970 glutamate/gamma-aminobutyrate family transporter YjeM (Escherichia coli ECRC98)
MIFTSVFGFANSPSAYYLMGYSAIPFYIFSALLFFIPFALMMAEMGAAYRKEEGGIYSWM
NNSVGPRFAFIGTFMWFSSYIIWMVSTSAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVG
LLAVAWMILVTVVASKGINKIARITAVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINF
LASPNPGYQSGLAMLSFVVFAIFAYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGY
SLAIFLWGVSTNWQQVLSNGSVNLGNITYVLMKSLGVTLGNALHLSPEASLSLGVWFARI
TGLSMFLAYTGAFFTLCYSPLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVF
ILLVSFGGGTASAFFNKLTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTRMSAM
IATVVVVLVVTFANVFTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRMANKP
ELALD